DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kat80 and AT1G52360

DIOPT Version :9

Sequence 1:	NP_523363.2	Gene:	kat80 / 32581	FlyBaseID:	FBgn0040207	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	NP_001185203.1	Gene:	AT1G52360 / 841666	AraportID:	AT1G52360	Length:	970	Species:	Arabidopsis thaliana

Alignment Length:	774	Identity:	144/774 - (18%)
Similarity:	276/774 - (35%)	Gaps:	162/774 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ISKIYDIKAHDSRVTSLDLGETGRVLVTGGEDRNVNLWAIGQN-ECFMSLTGHNRSIDCVRFAYK 71
            :.|:...:||...:..:.:..|...:::..:|..:.||...:. .|.....||:..:..|.|..|
plant   133 MDKVKVFEAHSDYIRCVAVHPTLPYVLSSSDDMLIKLWDWEKGWACTQIFEGHSHYVMQVTFNPK 197

  Fly    72 DNFVYSADDIG-IIRRWDLNSQKIYSTLNGHMKSVRTLDFNPSGE--YVVSGSNDTTVRLWDVQN 133
            |...:::..:. .|:.|:|.|.....||:.|.|.|..:|:...|:  |:::||:|.|.::||.|.
plant   198 DTNTFASASLDRTIKIWNLGSPDPNFTLDAHQKGVNCVDYFTGGDKPYLITGSDDHTAKVWDYQT 262

  Fly   134 ENNCIKVCRGHMSHVNSVKFSPDGLWIASAGLEGSILIWDIRKSKQIMEFIADPPVTAITCVQFH 198
            : :|::...||..:|::|                                          |  ||
plant   263 K-SCVQTLEGHTHNVSAV------------------------------------------C--FH 282

  Fly   199 PFEFLLAAGRVDGTVSIYDLEHQQLVSQTTHFYG-QAIRCITFSDNGECLFVGSSSGISVI--GW 260
            |...::..|..||||.|:.....:|  :.|..|| :.:..|.:..:...:.:|...|..::  |.
plant   283 PELPIIITGSEDGTVRIWHATTYRL--ENTLNYGLERVWAIGYIKSSRRVVIGYDEGTIMVKLGR 345

  Fly   261 E-PDRELDHI-KSTWSSLADMKVVNNKLICGCHEIDTVSINTISLDRVIPFYQPPNSLPNFKHNS 323
            | |...:|:. |..|:...:::..|.|.|...:|:.......:|:..:......|.||   |||.
plant   346 EIPVASMDNTGKIIWAKHNEIQTANIKSIGADYEVTDGERLPLSVKELGTCDLYPQSL---KHNP 407

  Fly   324 TNRKSFTRGNQKFRL---------SVGGAKPAQVQEEHEGDKSGLSSPNYSLEVVNEAVLESAET 379
            ..|.....|:.::.:         |.|.........|.|   ..:...:..:::.::...|....
plant   408 NGRFVVVCGDGEYIIYTALAWRNRSFGSGLEFVWSSEGE---CAVRESSSKIKIFSKNFQEKRSI 469

  Fly   380 SPMSSLPPVHLASMAGSSADLAPHHVVYGGAIDSALRQGKYSRVPDNMASYGSS----YGAIDTR 440
            .|..|.                  ..::||.:               :|...|.    |...:.|
plant   470 RPTFSA------------------EKIFGGTL---------------LAMCSSDFICFYDWAECR 501

  Fly   441 LMSLNEPSSLHKPDIYNLYPLDKNE------EADVQQLEFNLNDSNPPILNNYDNYEMAEDFPVN 499
            |:...:.:      :.|||..|..:      :.....|:||    ...:.:::|:....|:..|.
plant   502 LIQRIDVT------VKNLYWADSGDLVAIASDTSFYILKFN----RDLVTSHFDSGRPTEEEGVE 556

  Fly   500 QNLNYITNNYKPVPATSTI-------NASSK---SIKKTTTTTLHKRTTNNMAGAKQTSTGIFGG 554
            .....:..|.:.|.....:       |:|.|   .:....||..|......:.|...:.:.:|..
plant   557 DAFEVLHENDERVRTGIWVGDCFIYNNSSWKLNYCVGGEVTTMYHLDRPMYLLGYLASQSRVFLV 621

  Fly   555 SK----LSQVSSVSSMELHKLDDNMVLKKSSSSNVVNKNKRPMGSAQSQFSKENNQQKNINVEII 615
            .|    :.....:|.:|...|.....|.|  :|.::....:...::.:.|.:.....::. :||.
plant   622 DKEFNVIGYTLLLSLIEYKTLVMRGDLDK--ASEILPTIPKDQHNSVAHFLESRGMIEDA-LEIA 683

  Fly   616 TKPPMRSRTTLDMRTSHQAKTQEKQIHQQQPMNNRIIMDDHDFDMLSRSHEAVLQELSNRQSSLD 680
            |.|..|....:.:.....|  ||..:..|                 |.|....|.||:.....|.
plant   684 TDPDYRFELAIQLGRLEIA--QEIAVEVQ-----------------SESKWKQLGELAMSSGKLQ 729

  Fly   681 LLRHATR-SHDVLGALRQARSCGKSIFIDLLGAILEKPSSWNLDF-CMFVLPEIYELLQ 737
            :.....: :.|:.|.|....|.|.:..:..|..:.::....|:.| |:|:|.::.:.||
plant   730 MAEECMKYAMDLSGLLLLYSSLGDAEGVTKLATLAKEQGKNNVAFLCLFMLGKLEDCLQ 788

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kat80	NP_523363.2	Katanin_con80	667..803	CDD:290636	17/73 (23%)
		WD40	<4..330	CDD:225201	73/330 (22%)
		WD40	14..260	CDD:238121	54/252 (21%)
		WD40 repeat	22..58	CDD:293791	5/36 (14%)
		WD40 repeat	63..99	CDD:293791	9/36 (25%)
		WD40 repeat	106..142	CDD:293791	11/37 (30%)
		WD40 repeat	148..184	CDD:293791	2/35 (6%)
		WD40 repeat	192..228	CDD:293791	11/35 (31%)
		WD40 repeat	285..310	CDD:293791	4/24 (17%)
AT1G52360	NP_001185203.1	WD40	41..518	CDD:225201	91/476 (19%)
		WD40	61..341	CDD:238121	55/254 (22%)
		WD40 repeat	63..99	CDD:293791
		WD40 repeat	147..184	CDD:293791	5/36 (14%)
		WD40 repeat	189..226	CDD:293791	9/36 (25%)
		WD40 repeat	233..270	CDD:293791	11/37 (30%)
		WD40 repeat	276..308	CDD:293791	13/77 (17%)
		Coatomer_WDAD	364..808	CDD:281977	83/496 (17%)
		WD40 repeat	400..433	CDD:293791	8/35 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910