DRSC/TRiP Functional Genomics Resources

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Protein Alignment kat80 and Arpc1a

DIOPT Version :9

Sequence 1:NP_523363.2 Gene:kat80 / 32581 FlyBaseID:FBgn0040207 Length:819 Species:Drosophila melanogaster
Sequence 2:NP_112408.1 Gene:Arpc1a / 81824 RGDID:620834 Length:370 Species:Rattus norvegicus


Alignment Length:339 Identity:68/339 - (20%)
Similarity:133/339 - (39%) Gaps:76/339 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 SKIYDIKAHDSRVTSLDLGETGRVLVTGGEDRNVNLWAIGQNECF----MSLTGHNRSIDCVRFA 69
            :|.:::|.|:..:|.:|.......:||.|.|||..:|:  |.:..    :.:...||:...|:::
  Rat    43 TKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWS--QKDGIWKPTLVILRINRAATFVKWS 105

  Fly    70 YKDNFVYSADDIGIIRRWDLNSQKIYSTLNGHMK-----SVRTLDFNPSGEYVVSGSNDTTVRLW 129
            ..:|.........:|......|:..: .::.|:|     :|.:||::|:...:.:||.|...|::
  Rat   106 PLENKFAVGSGARLISVCYFESENDW-WVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVF 169

  Fly   130 DVQNENNCIKVC-------------------RGHMSHVNSVKFSPDGLWIASAGLEGSILIWDIR 175
            ....:....|..                   .|....|:.|.||..|..:|....:.::.:.|..
  Rat   170 SAYIKEVDEKPASTPWGSKMPFGQLMSEFGGSGTGGWVHGVSFSASGSRLAWVSHDSTVSVADAS 234

  Fly   176 KSKQI----MEFIADPPVTAITCVQFHPFEFLLAAG--------RVDGT-----VSIYDLEHQQL 223
            ||.|:    .||:   |:.:::.|..:.   ::|||        ..|..     ||..|:..|.:
  Rat   235 KSVQVSTLRTEFL---PLLSVSFVSENS---VVAAGHDCCPMLFNYDDRGCLTFVSKLDVPKQSI 293

  Fly   224 ---VSQTTHFYGQAIRCITFSDNG--ECLFVGSSSGISVIGWEPDRE---------LDHIKSTW- 273
               :|....|.....|..|...|.  |.|...|.:.:|:  :|.|::         :|...:.| 
  Rat   294 QRNMSAMERFRNMDKRATTEDRNTALETLHQNSITQVSI--YEVDKQDCRKFCTTGIDGAMTIWD 356

  Fly   274 -----SSLADMKVV 282
                 ||:..::::
  Rat   357 FKTLESSIQGLRIM 370

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kat80NP_523363.2 Katanin_con80 667..803 CDD:290636
WD40 <4..330 CDD:225201 68/339 (20%)
WD40 14..260 CDD:238121 61/295 (21%)
WD40 repeat 22..58 CDD:293791 10/39 (26%)
WD40 repeat 63..99 CDD:293791 4/35 (11%)
WD40 repeat 106..142 CDD:293791 8/54 (15%)
WD40 repeat 148..184 CDD:293791 11/39 (28%)
WD40 repeat 192..228 CDD:293791 10/51 (20%)
WD40 repeat 285..310 CDD:293791
Arpc1aNP_112408.1 WD 1 6..45 0/1 (0%)
WD40 repeat 11..50 CDD:293791 1/6 (17%)
WD40 46..>280 CDD:421866 48/242 (20%)
WD 2 50..89 11/40 (28%)
WD40 repeat 56..93 CDD:293791 10/38 (26%)
WD40 repeat 98..138 CDD:293791 5/40 (13%)
WD 3 140..179 8/38 (21%)
WD40 repeat 146..199 CDD:293791 8/52 (15%)
WD 4 202..241 11/38 (29%)
WD40 repeat 207..243 CDD:293791 10/35 (29%)
WD 5 244..284 8/45 (18%)
WD40 repeat 249..287 CDD:293791 7/40 (18%)
WD 6 322..365 9/44 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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