DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment kat80 and KATNBL1

DIOPT Version :9

Sequence 1:NP_523363.2 Gene:kat80 / 32581 FlyBaseID:FBgn0040207 Length:819 Species:Drosophila melanogaster
Sequence 2:NP_078989.1 Gene:KATNBL1 / 79768 HGNCID:26199 Length:304 Species:Homo sapiens


Alignment Length:250 Identity:44/250 - (17%)
Similarity:89/250 - (35%) Gaps:75/250 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   569 HKLDDNMV-LKKSSSSNVVNKNKRPMGSAQSQFSKENNQQKNINVEIITKPPMRSRTTLDMRTSH 632
            :|::|:.: |.:...||..|||.:.:..:..|.:...|:    .|....|.|.:.|..:..|   
Human    15 NKIEDHFIDLPRKKISNFTNKNMKEVKKSPKQLAAYINR----TVGQTVKSPDKLRKVIYRR--- 72

  Fly   633 QAKTQEKQIH----------QQQPMNNRIIMDD----------------HD-------------- 657
                  |::|          :|.|.:....|.:                ||              
Human    73 ------KKVHHPFPNPCYRKKQSPGSGGCDMANKENELACAGHLPEKLHHDSRTYLVNSSDSGSS 131

  Fly   658 ------------FDMLSRSHEAVLQELSNRQSSLDLLRHATRSH---DVLGALRQARSCGKSIFI 707
                        |..:|:.||.:.|.|.:|...|::.....|..   :::..|.:....|  :.:
Human   132 QTESPSSKYSGFFSEVSQDHETMAQVLFSRNMRLNVALTFWRKRSISELVAYLLRIEDLG--VVV 194

  Fly   708 D----LLGAILEKPSSWNLDFCMFVLPEIYELLQSQHKFHFTRACDTLRIILSNF 758
            |    |...:.|:....:|..|:.:||.:..||:|:.:.:.....:.|:.::..:
Human   195 DCLPVLTNCLQEEKQYISLGCCVDLLPLVKSLLKSKFEEYVIVGLNWLQAVIKRW 249

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kat80NP_523363.2 Katanin_con80 667..803 CDD:290636 18/98 (18%)
WD40 <4..330 CDD:225201
WD40 14..260 CDD:238121
WD40 repeat 22..58 CDD:293791
WD40 repeat 63..99 CDD:293791
WD40 repeat 106..142 CDD:293791
WD40 repeat 148..184 CDD:293791
WD40 repeat 192..228 CDD:293791
WD40 repeat 285..310 CDD:293791
KATNBL1NP_078989.1 Nuclear localization signal 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00768 26..33 2/6 (33%)
Nuclear localization signal 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00768 72..79 3/15 (20%)
Katanin_con80 153..296 CDD:372820 18/98 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
10.960

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