DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kat80 and Nup43

DIOPT Version :9

Sequence 1:	NP_523363.2	Gene:	kat80 / 32581	FlyBaseID:	FBgn0040207	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	XP_006227684.1	Gene:	Nup43 / 683983	RGDID:	1596513	Length:	378	Species:	Rattus norvegicus

Alignment Length:	151	Identity:	41/151 - (27%)
Similarity:	72/151 - (47%)	Gaps:	14/151 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LVTGGEDRNVNLWAIGQNECFMSLTGHNRS-IDCVRFAYKDNFVYSADDIGIIRRWDLNSQ---- 92
            :||.|||..:||:.:...|...::...:.| :..|.|......| :.:.||.::.||...|
  Rat   144 IVTVGEDGRINLFRVDHKEAVRTIDNADSSTLHAVTFLRTPEIV-TVNSIGQLKIWDFRQQGSEP 207

  Fly    93 -KIYSTLNGHMKSVRTLDFNPSGEYVV-SGSNDTTVRLWDVQNENNCIKVCRGHMSHVNSVKF-- 153
             :|.| |.|....:..:|.:|..::|| :|..|..:.:|||:.....:.:.:.|.:.:..|.|
  Rat   208 CQILS-LTGDRVPLHCVDRHPDQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHP 271

  Fly   154 -SPDGLWIASAGLEGSILIWD 173
             :||.|:..|.  :||:..||
  Rat   272 SNPDHLFTCSE--DGSLWHWD 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kat80	NP_523363.2	Katanin_con80	667..803	CDD:290636
		WD40	<4..330	CDD:225201	41/151 (27%)
		WD40	14..260	CDD:238121	41/151 (27%)
		WD40 repeat	22..58	CDD:293791	8/24 (33%)
		WD40 repeat	63..99	CDD:293791	10/40 (25%)
		WD40 repeat	106..142	CDD:293791	9/36 (25%)
		WD40 repeat	148..184	CDD:293791	10/29 (34%)
		WD40 repeat	192..228	CDD:293791
		WD40 repeat	285..310	CDD:293791
Nup43	XP_006227684.1	WD40	73..>293	CDD:421866	41/151 (27%)
		WD40 repeat	78..120	CDD:293791
		WD40 repeat	125..168	CDD:293791	8/23 (35%)
		WD40 repeat	175..212	CDD:293791	9/37 (24%)
		WD40 repeat	220..258	CDD:293791	9/37 (24%)
		WD40 repeat	266..303	CDD:293791	10/27 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910