DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kat80 and pex7

DIOPT Version :9

Sequence 1:	NP_523363.2	Gene:	kat80 / 32581	FlyBaseID:	FBgn0040207	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	NP_001343038.1	Gene:	pex7 / 5802962	PomBaseID:	SPAC17D4.01	Length:	308	Species:	Schizosaccharomyces pombe

Alignment Length:	223	Identity:	56/223 - (25%)
Similarity:	97/223 - (43%)	Gaps:	55/223 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALPRKLISKIYDIKAHDSRVTSLDLGETG-RVLVTGGEDRNVNLWA-----------IGQNECF 53
            :.:|.|.|.|   .|.|.:.:.::|..... |::|||..|..:.||.           .|.|...
pombe    89 LTMPSKPIHK---WKEHKAEIVAIDTNTVDRRIVVTGSWDGTIKLWLGNLPNSVQTLNNGSNSRI 150

  Fly    54 MSLTGHNRS--------------------------------IDCVRFAYKDN--FVYSADDIGII 84
            :::..|..|                                |.|:.:: |.|  .||:||:..::
pombe   151 LTVATHYSSPNLLGYTSSDGLCKFWDFRSSDKFMSIEIPNQITCMNWS-KSNHRMVYTADNNNLV 214

  Fly    85 RRWDL-NSQKIYSTLNGHMKSVRTL-DFNPSGEYVVSGSNDTTVRLWDVQNENNCIKVCRGHMSH 147
            ..:|: |.:...|.|:||..:||:: ..|.:.:.:.:.|.|.|.|::|.: :::||:....|...
pombe   215 YCYDIANLKTPLSVLSGHQLAVRSIKSSNSAHDLLATASYDMTSRIFDPE-QHSCIRKVDLHSEF 278

  Fly   148 VNSVKFSP--DGLWIASAGLEGSILIWD 173
            |..|.:|.  ||.||||.|.:.|:.||:
pombe   279 VRDVDWSDFGDGSWIASVGWDESLYIWN 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kat80	NP_523363.2	Katanin_con80	667..803	CDD:290636
		WD40	<4..330	CDD:225201	56/220 (25%)
		WD40	14..260	CDD:238121	52/210 (25%)
		WD40 repeat	22..58	CDD:293791	10/47 (21%)
		WD40 repeat	63..99	CDD:293791	11/38 (29%)
		WD40 repeat	106..142	CDD:293791	9/36 (25%)
		WD40 repeat	148..184	CDD:293791	13/28 (46%)
		WD40 repeat	192..228	CDD:293791
		WD40 repeat	285..310	CDD:293791
pex7	NP_001343038.1	WD40	35..>306	CDD:225201	55/221 (25%)
		WD40 repeat	65..101	CDD:293791	4/14 (29%)
		WD40 repeat	106..143	CDD:293791	8/36 (22%)
		WD40 repeat	151..185	CDD:293791	2/33 (6%)
		WD40 repeat	192..230	CDD:293791	11/38 (29%)
		WD40 repeat	236..273	CDD:293791	10/37 (27%)
		WD40 repeat	279..305	CDD:293791	11/25 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910