DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kat80 and wdr38

DIOPT Version :9

Sequence 1:	NP_523363.2	Gene:	kat80 / 32581	FlyBaseID:	FBgn0040207	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	NP_001017672.1	Gene:	wdr38 / 550366	ZFINID:	ZDB-GENE-050417-160	Length:	216	Species:	Danio rerio

Alignment Length:	186	Identity:	47/186 - (25%)
Similarity:	79/186 - (42%)	Gaps:	3/186 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 HNRSIDCVRFAYKDNFVYSADDIGIIRRWDLNSQKIYSTLNGHMKSVRTLDFNPSGEYVVSGSND 123
            |...::|..|:.....:.:..|.|.:..|..::.|:.::::||...|:...|:..|....|.|:|
Zfish    21 HKAEVNCCAFSPDCQLLLTCCDAGKLYLWKTSTAKLLASVSGHTGPVKCCVFSSDGRLFASASHD 85

  Fly   124 TTVRLWDVQNENNCIKVCRGHMSHVNSVKFSPDGLWIASAGLEGSILIWDIRKSKQIMEFIADPP 188
            .:||.| ..:...|......|...|.:|.|||||.|:.|.|.:...|||.|:....:.|.....
Zfish    86 CSVRTW-CNSSLKCTHTLTAHRRSVETVSFSPDGQWLLSGGWDNRALIWSIQSGALLEELKGHN- 148

  Fly   189 VTAITCVQFHPFEFLLAAGRVDGTVSIYDLEHQQLVSQTTHFYGQAIRCITFSDNG 244
             .|:....|......:|.|..|..|.::.|..:|..:.....:...:.|:.||..|
Zfish   149 -AAVQSSVFSSDSQSVATGSWDRAVRVWKLRDRQAEAVVLQGHLGNVACLCFSVAG 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kat80	NP_523363.2	Katanin_con80	667..803	CDD:290636
		WD40	<4..330	CDD:225201	47/186 (25%)
		WD40	14..260	CDD:238121	47/186 (25%)
		WD40 repeat	22..58	CDD:293791
		WD40 repeat	63..99	CDD:293791	6/35 (17%)
		WD40 repeat	106..142	CDD:293791	9/35 (26%)
		WD40 repeat	148..184	CDD:293791	15/35 (43%)
		WD40 repeat	192..228	CDD:293791	7/35 (20%)
		WD40 repeat	285..310	CDD:293791
wdr38	NP_001017672.1	WD40	<14..>208	CDD:225201	47/186 (25%)
		WD40	<15..200	CDD:238121	44/181 (24%)
		WD40 repeat	26..62	CDD:293791	6/35 (17%)
		WD40 repeat	67..103	CDD:293791	10/36 (28%)
		WD40 repeat	110..145	CDD:293791	14/34 (41%)
		WD40 repeat	152..188	CDD:293791	7/35 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0267
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900