DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kat80 and Poc1

DIOPT Version :9

Sequence 1:	NP_523363.2	Gene:	kat80 / 32581	FlyBaseID:	FBgn0040207	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	NP_001261799.1	Gene:	Poc1 / 39502	FlyBaseID:	FBgn0036354	Length:	403	Species:	Drosophila melanogaster

Alignment Length:	309	Identity:	73/309 - (23%)
Similarity:	123/309 - (39%)	Gaps:	76/309 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 HDSRVTSLDLGETGRVLVTGGEDRNVNLWAIGQNECFMSLTGHNRSIDCVRFAYKDNFVYSADDI 81
            |...:|.|..|..|..:.|...|..|.||.:.|....:....|:..::.|.::.|.|.|.||...
  Fly    17 HSGGITQLRFGPDGAQIATSSTDSTVILWNLNQAARCIRFASHSAPVNGVAWSPKGNLVASAGHD 81

  Fly    82 GIIRRWDLNSQKIYSTLNGHMKSVRTLDFNPSGEYVVSGSNDTTVRLWDV---------QNENNC 137
            ..::.|:...:.:......|.|:||::||:.:|..:::.|:|.:.::|.|         ..:||.
  Fly    82 RTVKIWEPKLRGVSGEFVAHSKAVRSVDFDSTGHLMLTASDDKSAKIWRVARRQFVSSFAQQNNW 146

  Fly   138 IKVCRGHMSHVNSVKFSPDGLWIASAGLEGSILIWDIRKSKQIMEF---------IADPP----- 188
            ::          |.||||:|..:|:|..:.|:.|:|:...:.:..|         :|..|
  Fly   147 VR----------SAKFSPNGKLVATASDDKSVRIYDVDSGECVRTFTEERAAPRQLAWHPWGNML 201

  Fly   189 VTAITC--------------------------VQFHPFEFLLAAGRVDGTVSIYD-LEHQQLVSQ 226
            ..|:.|                          |.|||....|.:|..|.|:.|.| ||.:.:.:.
  Fly   202 AVALGCNRIKIFDVSGSQLLQLYVVHSAPVNDVAFHPSGHFLLSGSDDRTIRILDLLEGRPIYTL 266

  Fly   227 TTHFYGQAIRCITFSDNGECLFVGSSSGISVIGWEPDRELDHIKSTWSS 275
            |.|  ..|:..:.||.:|:....|.|          ||:|    ..|.|
  Fly   267 TGH--TDAVNAVAFSRDGDKFATGGS----------DRQL----LVWQS 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kat80	NP_523363.2	Katanin_con80	667..803	CDD:290636
		WD40	<4..330	CDD:225201	73/309 (24%)
		WD40	14..260	CDD:238121	68/292 (23%)
		WD40 repeat	22..58	CDD:293791	10/35 (29%)
		WD40 repeat	63..99	CDD:293791	7/35 (20%)
		WD40 repeat	106..142	CDD:293791	10/44 (23%)
		WD40 repeat	148..184	CDD:293791	12/44 (27%)
		WD40 repeat	192..228	CDD:293791	13/62 (21%)
		WD40 repeat	285..310	CDD:293791
Poc1	NP_001261799.1	WD40	10..298	CDD:238121	71/306 (23%)
		WD40	14..388	CDD:225201	73/309 (24%)
		WD40 repeat	22..58	CDD:293791	10/35 (29%)
		WD40 repeat	63..99	CDD:293791	7/35 (20%)
		WD40 repeat	106..140	CDD:293791	8/33 (24%)
		WD40 repeat	147..183	CDD:293791	11/45 (24%)
		WD40 repeat	189..224	CDD:293791	4/34 (12%)
		WD40 repeat	231..254	CDD:293791	8/22 (36%)
		WD40 repeat	273..297	CDD:293791	8/37 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910