DRSC/TRiP Functional Genomics Resources

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Protein Alignment kat80 and POC1B

DIOPT Version :9

Sequence 1:NP_523363.2 Gene:kat80 / 32581 FlyBaseID:FBgn0040207 Length:819 Species:Drosophila melanogaster
Sequence 2:NP_758440.1 Gene:POC1B / 282809 HGNCID:30836 Length:478 Species:Homo sapiens


Alignment Length:262 Identity:74/262 - (28%)
Similarity:119/262 - (45%) Gaps:5/262 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 SKIYDIKAHDSRVTSLDLGETGRVLVTGGEDRNVNLWAIGQNECFMSLTGHNRSIDCVRFAYKDN 73
            ::.|....|...|||:.....|.:|.:...||.|.||...:...|.....|...:..|.|:....
Human    51 ARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQ 115

  Fly    74 FVYSADDIGIIRRWDLNSQKIYSTLNGHMKSVRTLDFNPSGEYVVSGSNDTTVRLWDVQNENNCI 138
            |:.:|.:...|:.|.:..|:...:|..|...||...|:|.|..:||.|.|.|:::||..|: .|:
Human   116 FLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNK-QCV 179

  Fly   139 KVCRGHMSHVNSVKFSPDGLWIASAGLEGSILIWDIRKSKQIMEFIADPPVTAITCVQFHPFEFL 203
            ......:...|.|.|:|.|..|||||.:.::.:||:|.:|.:..:....  ..:.|:.|||....
Human   180 NNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHS--GGVNCISFHPSGNY 242

  Fly   204 LAAGRVDGTVSIYDLEHQQLVSQTTHFYGQAIRCITFSDNGECLFVGSSSGISVIGWEPDRELDH 268
            |.....|||:.|.||...:|: .|...:...:..::||..|| ||....:...|:.|..:.:..|
Human   243 LITASSDGTLKILDLLEGRLI-YTLQGHTGPVFTVSFSKGGE-LFASGGADTQVLLWRTNFDELH 305

  Fly   269 IK 270
            .|
Human   306 CK 307

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kat80NP_523363.2 Katanin_con80 667..803 CDD:290636
WD40 <4..330 CDD:225201 74/262 (28%)
WD40 14..260 CDD:238121 70/245 (29%)
WD40 repeat 22..58 CDD:293791 10/35 (29%)
WD40 repeat 63..99 CDD:293791 7/35 (20%)
WD40 repeat 106..142 CDD:293791 13/35 (37%)
WD40 repeat 148..184 CDD:293791 14/35 (40%)
WD40 repeat 192..228 CDD:293791 12/35 (34%)
WD40 repeat 285..310 CDD:293791
POC1BNP_758440.1 WD40 10..298 CDD:238121 71/251 (28%)
WD 1 16..55 0/3 (0%)
WD40 repeat 21..58 CDD:293791 1/6 (17%)
WD 2 58..99 12/40 (30%)
WD40 repeat 63..100 CDD:293791 11/36 (31%)
WD 3 101..139 8/37 (22%)
WD40 repeat 106..142 CDD:293791 8/35 (23%)
WD 4 142..181 15/39 (38%)
WD40 repeat 147..182 CDD:293791 14/35 (40%)
WD 5 183..223 14/39 (36%)
WD40 repeat 190..225 CDD:293791 14/34 (41%)
WD 6 226..265 12/41 (29%)
WD40 repeat 231..267 CDD:293791 13/36 (36%)
WD 7 268..307 9/39 (23%)
WD40 repeat 273..299 CDD:293791 8/26 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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