DRSC/TRiP Functional Genomics Resources

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Protein Alignment kat80 and wdr-5.2

DIOPT Version :9

Sequence 1:NP_523363.2 Gene:kat80 / 32581 FlyBaseID:FBgn0040207 Length:819 Species:Drosophila melanogaster
Sequence 2:NP_510394.1 Gene:wdr-5.2 / 181540 WormBaseID:WBGene00010572 Length:395 Species:Caenorhabditis elegans


Alignment Length:294 Identity:79/294 - (26%)
Similarity:135/294 - (45%) Gaps:27/294 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 KLISKIYDIKAHDSRVTSLDLGETGRVLVTGGEDRNVNLWAIGQNECFM---SLTGHNRSIDCVR 67
            ||:::|.:  ||...::.:.....||.:.:|..|.::.:|.:.    |:   :|.||...|:...
 Worm    97 KLVAEIPN--AHKKSISGIKFSPDGRYMGSGSADCSIKIWRMD----FVYEKTLMGHRLGINEFS 155

  Fly    68 FAYKDNFVYSADDIGIIRRWDLNSQKIYSTLNGHMKSVRTLDFNPSGEYVVSGSNDTTVRLWDVQ 132
            ::.....:.|..|..:::.:|::|.:...||.||...|....|||||..:.|||.|.|:|:|..:
 Worm   156 WSSDSKLIVSCSDDKLVKVFDVSSGRCVKTLKGHTNYVFCCCFNPSGTLIASGSFDETIRIWCAR 220

  Fly   133 NENNCIKVCRGHMSHVNSVKFSPDGLWIASAGLEGSILIWDIRKSKQIMEFIAD--PPVTAITCV 195
            |.|....: .||...|:||.|:.||.::||...:|.:.|||......:...|.:  ||   ||.|
 Worm   221 NGNTIFSI-PGHEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPP---ITHV 281

  Fly   196 QFHPFEFLLAAGRVDGTVSIYDLEHQQLVSQ-TTHFYGQAIRCITFSDNGECLFVGSSSGISVIG 259
            :|.|....:.|..::.|:.::|.:..:::.: |.|...:......||..|....|..|....|..
 Worm   282 KFSPNGKYILASNLNNTLKLWDYQKLRVLKEYTGHENSKYCVAANFSVTGGKWIVSGSEDHKVYI 346

  Fly   260 WE-PDRELDHIKSTWSSLADMKVVNNKLIC-GCH 291
            |. ..||:         |..:...|..::| .||
 Worm   347 WNLQTREI---------LQTLDGHNTAVMCTDCH 371

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kat80NP_523363.2 Katanin_con80 667..803 CDD:290636
WD40 <4..330 CDD:225201 79/294 (27%)
WD40 14..260 CDD:238121 68/251 (27%)
WD40 repeat 22..58 CDD:293791 7/38 (18%)
WD40 repeat 63..99 CDD:293791 6/35 (17%)
WD40 repeat 106..142 CDD:293791 14/35 (40%)
WD40 repeat 148..184 CDD:293791 12/35 (34%)
WD40 repeat 192..228 CDD:293791 8/36 (22%)
WD40 repeat 285..310 CDD:293791 3/8 (38%)
wdr-5.2NP_510394.1 WWbp <1..87 CDD:304964
WD40 <104..395 CDD:225201 76/287 (26%)
WD40 106..392 CDD:238121 75/283 (27%)
WD40 repeat 110..146 CDD:293791 7/39 (18%)
WD40 repeat 152..188 CDD:293791 6/35 (17%)
WD40 repeat 193..229 CDD:293791 15/36 (42%)
WD40 repeat 236..271 CDD:293791 11/34 (32%)
WD40 repeat 278..314 CDD:293791 8/35 (23%)
WD40 repeat 322..359 CDD:293791 10/45 (22%)
WD40 repeat 365..391 CDD:293791 3/7 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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