DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kat80 and Y111B2A.12

DIOPT Version :9

Sequence 1:	NP_523363.2	Gene:	kat80 / 32581	FlyBaseID:	FBgn0040207	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	NP_001255175.1	Gene:	Y111B2A.12 / 176680	WormBaseID:	WBGene00013735	Length:	417	Species:	Caenorhabditis elegans

Alignment Length:	216	Identity:	47/216 - (21%)
Similarity:	96/216 - (44%)	Gaps:	9/216 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LPRKLI-SKIYDIKAHDSRVTSLDLGETGRVLVTGGEDRNVNLWAIGQNECFMSL-TGHNRSIDC 65
            :|.::| ..:..::||.....::.|. :.|.|.|||||....|:...|:|....| ..|..|:..
Worm    42 VPAEIIDDSLMSLQAHAQDCFTVALA-SNRWLATGGEDDVAFLFDQNQSESEPVLKVEHKDSVTQ 105

  Fly    66 VRFAYKDNFVYSADDIGIIRRWDLNSQKIYSTLNGHMKSVRTLDFNPSGEYVVSGSNDTTVRLWD 130
            |.|.:.:..:.:.|..|.|...::.::|:.:.:: ....:..:.::.:.:.:.:|..|..:.:|.
Worm   106 VMFNHSETLLATGDLSGKIMISEMATKKVRAEID-ECNDLEWMCWHQTADILFAGDKDGILWMWL 169

  Fly   131 VQNENNC-IKVCRGHMSHVNSVKFSPDGLWIASAGLEGSILIWDIRKSKQIMEFIADPPVTAITC 194
            :.|:... .||..|:.|...:....|||..|.....:|.:.:|.:|:......:...|    ||.
Worm   170 IGNKGIAQSKVYAGNGSSCTTGCLMPDGKRIMCGYSDGIVRLWLLREETSTHLYFHSP----ITA 230

  Fly   195 VQFHPFEFLLAAGRVDGTVSI 215
            :..|..:.:...|...|||::
Worm   231 IDHHVTQTVAIIGTQSGTVNV 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kat80	NP_523363.2	Katanin_con80	667..803	CDD:290636
		WD40	<4..330	CDD:225201	47/215 (22%)
		WD40	14..260	CDD:238121	45/204 (22%)
		WD40 repeat	22..58	CDD:293791	12/36 (33%)
		WD40 repeat	63..99	CDD:293791	6/35 (17%)
		WD40 repeat	106..142	CDD:293791	6/36 (17%)
		WD40 repeat	148..184	CDD:293791	7/35 (20%)
		WD40 repeat	192..228	CDD:293791	7/24 (29%)
		WD40 repeat	285..310	CDD:293791
Y111B2A.12	NP_001255175.1	WD40	54..372	CDD:392136	45/204 (22%)
		WD40 repeat	104..139	CDD:293791	6/34 (18%)
		WD40 repeat	144..182	CDD:293791	6/37 (16%)
		WD40 repeat	189..231	CDD:293791	10/45 (22%)
		WD40 repeat	238..294	CDD:293791	4/14 (29%)
		WD40 repeat	302..338	CDD:293791
		WD40 repeat	345..371	CDD:293791
		WD40 repeat	389..416	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910