DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kat80 and AgaP_AGAP011387

DIOPT Version :9

Sequence 1:	NP_523363.2	Gene:	kat80 / 32581	FlyBaseID:	FBgn0040207	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	XP_317937.4	Gene:	AgaP_AGAP011387 / 1278314	VectorBaseID:	AGAP011387	Length:	435	Species:	Anopheles gambiae

Alignment Length:	298	Identity:	61/298 - (20%)
Similarity:	115/298 - (38%)	Gaps:	66/298 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 HDSRVTSLDLGETGRVLVTGGEDRNVNLWAIGQNECFMSLTGHNRSIDCVRFAYKDNFVYSADDI 81
            |.:.|....|..|..:.||||||....:|.|...|....:|.|:.|:..|.|:|..:||.:.|..
Mosquito   103 HTAPVFCGALHPTEELAVTGGEDDKAYVWHIRTGEVLHEVTNHSDSVVAVGFSYDGSFVATGDMA 167

  Fly    82 GIIR----------------------RWDLNSQ---------KIY---------STLNGHMKSVR 106
            |.|:                      ||...:.         ::|         ..|.||.....
Mosquito   168 GYIQVFKVSQNYRQVWEFTVGDMGWMRWHTGANVLMAGCEAGEVYVWRIPSGDCKVLPGHEARTE 232

  Fly   107 TLDFNPSGEYVVSGSNDTTVRLWDVQNENNCIKV--CRGHMSHVNSVKFSPDGLWIASAGLEGSI 169
            :.:....|:.::.|..:..|:|||:::....::|  ..||..::.::....||....:...:||:
Mosquito   233 SAELLHDGKRLLVGYGNGHVKLWDLKSGTPLLEVDSTVGHKENITALAADQDGQLFVTGWEDGSL 297

  Fly   170 LIWDIRKSKQIMEFIA--DPPVTAITCVQFHPFEFLLAA-GRVDGTVSIYDLEHQQLVSQTTHFY 231
            .:  :.....:.:.:|  :.|:.:: .|.:..||..:|| |.:.|.::|:|...|.
Mosquito   298 YL--MGPGGVLGQLVAPNEYPIESV-LVDYPGFEMKVAASGTLQGKLTIWDAARQT--------- 350

  Fly   232 GQAIRCITFSDNG--------ECLFVGSSSGISVIGWE 261
             :.:.|...:.||        :......:.|..:.||:
Mosquito   351 -KRVECEDDNPNGITKLVWLKDFTICAGTLGGWIKGWD 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kat80	NP_523363.2	Katanin_con80	667..803	CDD:290636
		WD40	<4..330	CDD:225201	61/298 (20%)
		WD40	14..260	CDD:238121	59/295 (20%)
		WD40 repeat	22..58	CDD:293791	11/35 (31%)
		WD40 repeat	63..99	CDD:293791	11/75 (15%)
		WD40 repeat	106..142	CDD:293791	7/37 (19%)
		WD40 repeat	148..184	CDD:293791	4/35 (11%)
		WD40 repeat	192..228	CDD:293791	10/36 (28%)
		WD40 repeat	285..310	CDD:293791
AgaP_AGAP011387	XP_317937.4	WD40	<99..431	CDD:225201	61/298 (20%)
		WD40	99..429	CDD:238121	61/298 (20%)
		WD40 repeat	107..144	CDD:293791	12/36 (33%)
		WD40 repeat	150..187	CDD:293791	8/36 (22%)
		WD40 repeat	191..225	CDD:293791	3/33 (9%)
		WD40 repeat	232..267	CDD:293791	6/34 (18%)
		WD40 repeat	276..338	CDD:293791	12/64 (19%)
		WD40 repeat	363..398	CDD:293791	3/25 (12%)
		WD40 repeat	405..428	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910