DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kat80 and AgaP_AGAP006264

DIOPT Version :9

Sequence 1:	NP_523363.2	Gene:	kat80 / 32581	FlyBaseID:	FBgn0040207	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	XP_001688840.1	Gene:	AgaP_AGAP006264 / 1276918	VectorBaseID:	AGAP006264	Length:	321	Species:	Anopheles gambiae

Alignment Length:	182	Identity:	45/182 - (24%)
Similarity:	86/182 - (47%)	Gaps:	8/182 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SKIYDIKAHDSRVTSLDLGET--GRVLVTGGEDRNVNLWAIGQNECFMSLTGHNRSI-DCVRFAY 70
            |.:|  :.|...:.|:|..:.  .::.::...|..|.:|...:|....:..||.:.: ..|..|:
Mosquito   101 SMVY--REHKKEIYSVDWSKVPYEQLFISASWDSTVKIWDPIRNNSLSTYIGHTQLVYSAVFAAH 163

  Fly    71 KDNFVYSADDIGIIRRWDLNSQKI-YSTLNGHMKSVRTLDF-NPSGEYVVSGSNDTTVRLWDVQN 133
            ..|...|....|.::.||:....: .:::..|...|.|:|: ......:.:|::|..:|:||::|
Mosquito   164 IPNTFASVSGDGFLKIWDILCYDLPIASIKAHDGEVLTVDWCKHDSNILATGASDGLIRIWDLRN 228

  Fly   134 ENNCIKVCRGHMSHVNSVKFSPDGLWI-ASAGLEGSILIWDIRKSKQIMEFI 184
            ....|...:|:...|..|:|||....: ||.|.:.:..|||.:||.:.:|.|
Mosquito   229 FGVPITELKGNEFAVRKVQFSPHNFSVLASVGYDFTTRIWDFKKSNEAIETI 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kat80	NP_523363.2	Katanin_con80	667..803	CDD:290636
		WD40	<4..330	CDD:225201	45/182 (25%)
		WD40	14..260	CDD:238121	43/177 (24%)
		WD40 repeat	22..58	CDD:293791	6/37 (16%)
		WD40 repeat	63..99	CDD:293791	7/37 (19%)
		WD40 repeat	106..142	CDD:293791	9/36 (25%)
		WD40 repeat	148..184	CDD:293791	14/36 (39%)
		WD40 repeat	192..228	CDD:293791
		WD40 repeat	285..310	CDD:293791
AgaP_AGAP006264	XP_001688840.1	WD40	6..>313	CDD:225201	45/182 (25%)
		WD40 repeat	12..58	CDD:293791
		WD40	61..313	CDD:295369	45/182 (25%)
		WD40 repeat	64..106	CDD:293791	2/6 (33%)
		WD40 repeat	112..150	CDD:293791	6/37 (16%)
		WD40 repeat	155..192	CDD:293791	7/36 (19%)
		WD40 repeat	200..237	CDD:293791	9/36 (25%)
		WD40 repeat	243..281	CDD:293791	15/38 (39%)
		WD40 repeat	287..314	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910