DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kat80 and AgaP_AGAP009506

DIOPT Version :9

Sequence 1:	NP_523363.2	Gene:	kat80 / 32581	FlyBaseID:	FBgn0040207	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	XP_310190.3	Gene:	AgaP_AGAP009506 / 1271405	VectorBaseID:	AGAP009506	Length:	350	Species:	Anopheles gambiae

Alignment Length:	219	Identity:	59/219 - (26%)
Similarity:	105/219 - (47%)	Gaps:	11/219 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SKIYDIKAHDSRVTSLDLGETG-RVLVTGGEDRNVNLWAIGQNECFMSLTGHNRSIDCVRFAYKD 72
            ::|..:|.|...|.|......| .::|:|.:|.::.:|. .:....:|...:...:..|.|....
Mosquito   134 TRIRKLKGHTHFVNSCSGARRGPTLIVSGSDDASIKIWD-ARKRHVVSTFDNTYQVTAVCFNDTA 197

  Fly    73 NFVYSADDIGIIRRWDLNSQKIYSTLNGHMKSVRTLDFNPSGEYVVSGSNDTTVRLWDVQ---NE 134
            ..|.|......|:.||:..::|...|.||..:|..|..:|.|.||:|.|.|.|:|:||::   ..
Mosquito   198 EQVVSGGIDNEIKVWDIRKKEILYRLRGHTDTVTGLSLSPDGSYVLSNSMDNTLRIWDIRPYVPA 262

  Fly   135 NNCIKVCRGHMSHVNS----VKFSPDGLWIASAGLEGSILIWDIRKSKQIMEFIADPPVTAITCV 195
            ..|:||..||..:...    ..:|||||.|::...:..:.||| ..|::|: :.......::..:
Mosquito   263 ERCVKVFTGHQHNFEKNLLRCAWSPDGLKISAGSADRFVYIWD-TTSRRIL-YKLPGHNGSVNDI 325

  Fly   196 QFHPFEFLLAAGRVDGTVSIYDLE 219
            .|||.|.::.:|..|.|:.:.::|
Mosquito   326 DFHPTEPIIVSGSSDKTLYLGEIE 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kat80	NP_523363.2	Katanin_con80	667..803	CDD:290636
		WD40	<4..330	CDD:225201	59/219 (27%)
		WD40	14..260	CDD:238121	58/214 (27%)
		WD40 repeat	22..58	CDD:293791	7/36 (19%)
		WD40 repeat	63..99	CDD:293791	8/35 (23%)
		WD40 repeat	106..142	CDD:293791	15/38 (39%)
		WD40 repeat	148..184	CDD:293791	11/39 (28%)
		WD40 repeat	192..228	CDD:293791	8/28 (29%)
		WD40 repeat	285..310	CDD:293791
AgaP_AGAP009506	XP_310190.3	WD40	52..>345	CDD:225201	58/213 (27%)
		WD40	54..345	CDD:238121	58/213 (27%)
		WD40 repeat	61..99	CDD:293791
		WD40 repeat	105..141	CDD:293791	1/6 (17%)
		WD40 repeat	146..183	CDD:293791	8/37 (22%)
		WD40 repeat	189..224	CDD:293791	8/34 (24%)
		WD40 repeat	230..270	CDD:293791	16/39 (41%)
		WD40 repeat	280..316	CDD:293791	11/37 (30%)
		WD40 repeat	322..345	CDD:293791	7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910