DRSC/TRiP Functional Genomics Resources

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Protein Alignment kat80 and Fbxw11

DIOPT Version :9

Sequence 1:NP_523363.2 Gene:kat80 / 32581 FlyBaseID:FBgn0040207 Length:819 Species:Drosophila melanogaster
Sequence 2:NP_598776.1 Gene:Fbxw11 / 103583 MGIID:2144023 Length:563 Species:Mus musculus


Alignment Length:283 Identity:74/283 - (26%)
Similarity:114/283 - (40%) Gaps:87/283 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 KLISKIYD--IKAHDSRVTSLD-----LGETG---------RVLVTGGEDRNVNLWAIGQNECFM 54
            |:||.:.|  ||..|.  :||:     .|.||         ||:|||..|..|.:|.:...|...
Mouse   273 KIISGLRDNSIKIWDK--SSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLN 335

  Fly    55 SLTGHNRSIDCVRFA-----------------------------------------YKDNFVYSA 78
            :|..||.::..:||:                                         :.|.::.||
Mouse   336 TLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSA 400

  Fly    79 DDIGIIRRWDLNSQKIYSTLNGHMKSVRTLDFNPSGEYVVSGSNDTTVRLWDVQNENNCIKVCRG 143
            .....|:.|..::.:...|||||.:.:..|.:.  ...|||||:|.|:||||::. ..|::|..|
Mouse   401 SGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYR--DRLVVSGSSDNTIRLWDIEC-GACLRVLEG 462

  Fly   144 HMSHVNSVKFSPDGLWIASAGLEGSILIWDIRKSKQIMEFIADPPVTAIT-C------------- 194
            |...|..::|  |...|.|...:|.|.:||::.:       .||...|.| |             
Mouse   463 HEELVRCIRF--DNKRIVSGAYDGKIKVWDLQAA-------LDPRAPASTLCLRTLVEHSGRVFR 518

  Fly   195 VQFHPFEFLLAAGRVDGTVSIYD 217
            :||.  ||.:.:...|.|:.|:|
Mouse   519 LQFD--EFQIISSSHDDTILIWD 539

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kat80NP_523363.2 Katanin_con80 667..803 CDD:290636
WD40 <4..330 CDD:225201 74/283 (26%)
WD40 14..260 CDD:238121 70/273 (26%)
WD40 repeat 22..58 CDD:293791 15/49 (31%)
WD40 repeat 63..99 CDD:293791 8/76 (11%)
WD40 repeat 106..142 CDD:293791 14/35 (40%)
WD40 repeat 148..184 CDD:293791 9/35 (26%)
WD40 repeat 192..228 CDD:293791 10/40 (25%)
WD40 repeat 285..310 CDD:293791
Fbxw11NP_598776.1 Beta-TrCP_D 99..137 CDD:403372
F-box-like 141..188 CDD:403981
WD40 261..539 CDD:238121 73/281 (26%)
WD40 repeat 264..299 CDD:293791 9/27 (33%)
WD40 repeat 305..339 CDD:293791 10/33 (30%)
WD40 repeat 344..381 CDD:293791 2/36 (6%)
WD40 repeat 388..421 CDD:293791 6/32 (19%)
WD40 repeat 427..461 CDD:293791 14/36 (39%)
WD40 repeat 467..510 CDD:293791 14/51 (27%)
WD40 repeat 516..538 CDD:293791 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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