Protein Alignment disco and disco-r

DIOPT Version :10

• Sequence 1: NP_523362.2
• Gene: disco / 32579
• FlyBaseID: FBgn0000459
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_727938.1
• Gene: disco-r / 64875
• FlyBaseID: FBgn0285879
• Length: 1311
• Species: Drosophila melanogaster
• Alignment Length: 892
• Identity: 231/892 - (25%)
• Similarity: 326/892 - (36%)
• Gaps: 400/892 - (44%)

  Fly     5 MNPF----MSPAYLLG-----------------HGPHSHQHVHSH-------------------L 29
            |.||    :|.|..||                 |..||.|..|.|                   .
  Fly   278 MQPFDFRKISSAAALGAFGGPLPLPQSPTEFGQHHHHSQQQQHQHHLHRNQFFNAMAMAYHLPPP 342

  Fly    30 PSHPQPNAASPASSPGG--------SSGSGSGSAAGSGTGSG----------------------- 63
            |..|.|::.||.|.|.|        .|||||||.:|||:.||
  Fly   343 PPPPPPDSRSPPSPPPGVGQYQHQAGSGSGSGSGSGSGSSSGAGSVDDSAGKQQRNSDKVSASGS 407

  Fly    64 -----------------SSLK----------------------PRRWGSPPINLAGQFINPATGK 89
                             ||.|                      .|:|||.|.||..|||||.|||
  Fly   408 CSSSQRMTRLALSSNMRSSRKTPHSPGGGGAGGNGGSVGGGGGKRQWGSMPANLGTQFINPVTGK 472

  Fly    90 KRVQCSICFKTFCDKGALKIHFSAVHLREMHKCTVEGCNMVFSSRRSRNRHSANPNPKLHSPHIR 154
            |||||::|.||||||||||||||||||||||||||:||:|:||||||||||||||||||||||:|
  Fly   473 KRVQCNVCLKTFCDKGALKIHFSAVHLREMHKCTVDGCSMMFSSRRSRNRHSANPNPKLHSPHLR 537

  Fly   155 RKISPHDGRTAQQFPVFSPGTAAAAAAVAGRLPV-AFPGLLPPPPPHHGHHPYVMFGGQAG---- 214
            |||||||||:||..|:.   ..|....:||..|. :||.|.|||...|    :.|.|..||
  Fly   538 RKISPHDGRSAQPHPLL---LQAPNGLMAGLAPFGSFPLLTPPPDLRH----HAMGGSGAGSGAG 595

  Fly   215 ------LHG--------------------------------------LGLLSTGCQDPDSGSVDN 235
                  .||                                      :|:...|  |.|....|.
  Fly   596 VGALELKHGQDYLQRSYLDAGRFEGQRRKLAMENEHTEDEDDDEILEVGIHMAG--DDDDDEADG 658

  Fly   236 EQDADPEDDNDFVYVDMQANSSSPAASSEDQEEHERDNEQDEEMHCSLSLASSSS---------- 290
            ::|.|.:|.:..|.|..:.:|    ...:.:.:::.:||.||....|.|..||.|
  Fly   659 DEDEDDDDPDGIVVVGDEIDS----MPLDHENDNDNENENDESDERSTSAVSSLSQTKEQSSPGK 719

  Fly   291 ------------------------------------IAADE-ERAADQPL--------------- 303
                                                :||:: :|.:..|:
  Fly   720 VVQSGLEECHTYAHAHAHALTHGHAHSLGHAHALAQMAANKRKRKSQNPVRCPVQSDENSGENSI 784

  Fly   304 ------DFSLHKRR---------------------------------------KSEQDREQEQEQ 323
                  |.|:.|.|                                       |:|||.|||.:|
  Fly   785 DYDVAADLSIKKVRLPAQAAASAKESEVGESTKSIPSPPLTPYGDLRPVGLCIKTEQDHEQELDQ 849

  Fly   324 EQEREREAEKEQEQDVE-------------------SDKEHEPEQEHELEREKRSPSDAFSMD-- 367
            ||.:||:.|:|||.:.:                   :|||.:.|::     |:.||....::|
  Fly   850 EQGQERKREQEQEPEPDPVATASKSEMKLEEQETRPADKEDDNEED-----EQVSPPVVTTLDLS 909

  Fly   368 ----------------------------QLLGKRKRHDSTASSSACSTAAASSASSSSASASANP 404
                                        :|:|   ..:|.|..|:..||..::.::::.:.:.|
  Fly   910 RAAAAIKLEPLEEINYEADENRYVRIKQELMG---GDESLAEESSDKTANHNNNNNNNNNININ- 970

  Fly   405 PQTSIKMDLDPDSDSAYMTSRRQMLPLPVLDLE---EHHHLRLLQTQMFAAAAAAAATSQAPPTA 466
              .|::::.|...:::.:..|.   |.|..::|   ||.|....:|::           :.|..
  Fly   971 --NSVRLESDNGLEASELEERE---PEPETEIEPEHEHEHEPEPETEV-----------EVPEV- 1018

  Fly   467 FLPAGSPVDLAKDSPPMWSLLSEMYRSML-LKTQHQQYN---HH-------------HQLQQQHQ 514
                  |:|  |::|...:...|::::.. |||.||..:   ||             .:.:.:|.
  Fly  1019 ------PID--KENPLKCTACGEIFQNHFHLKTHHQSVHLKLHHKCNIDGCNAAFPSKRSRDRHS 1075

  Fly   515 QEQHHH---LTLSHHHQEQHH---------------HLGHHHMGHHH 543
            ...:.|   |:.|..|...|.               :|.::..|.||
  Fly  1076 SNLNLHRKLLSTSDDHGLLHAPVMPATDPLLELMSLNLNNNKSGFHH 1122

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
disco	NP_523362.2	None
disco-r	NP_727938.1	C2H2 Zn finger	1028..1053	CDD:275370	6/24 (25%)
		C2H2 Zn finger	1056..1083	CDD:275370	2/26 (8%)