DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment disco and Bnc2

DIOPT Version :9

Sequence 1:NP_001033847.1 Gene:disco / 32579 FlyBaseID:FBgn0000459 Length:568 Species:Drosophila melanogaster
Sequence 2:XP_017175693.1 Gene:Bnc2 / 242509 MGIID:2443805 Length:1156 Species:Mus musculus


Alignment Length:459 Identity:122/459 - (26%)
Similarity:174/459 - (37%) Gaps:150/459 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    69 RRWGSPPINLAGQFINPATGKKRVQCSICFKTFCDKGALKIHFSAVHLREMHKCTVEGCNMVFSS 133
            ||.||            |:.|.||.|:.|.|||.|||.||||::||||:..|:||:|||||||||
Mouse   465 RRMGS------------ASRKGRVFCNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSS 517

  Fly   134 RRSRNRHSANPNPKLHSPHIRRK------------ISPHDGRTAQQFPVFSPG-------TAAAA 179
            .||||||||||||:||.|.:|..            .:|....|.....:.|||       |....
Mouse   518 LRSRNRHSANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLTLTSPGRPPMGFTTPPLD 582

  Fly   180 AAVAGRLP--VAFPGL-------------------------LP--------------PPPPHHGH 203
            ..:...||  :.|.||                         ||              ||||....
Mouse   583 PVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGTIEQHPPPPSEPI 647

  Fly   204 HPYVMFGGQAGLHGLGLLSTGCQDPDSGSVDNEQDADPEDDNDFVYVDMQANSSSPAASSEDQEE 268
            .|.||.              |..:|   |.|......|...:..|.::.:...::.....||.:.
Mouse   648 VPAVMM--------------GTHEP---SADLAPKKKPRKSSMPVKIEKEIIDTADEFDDEDDDP 695

  Fly   269 HERD---NEQDEEMHCSLSLASSSSIAADEERAADQPLDFSLHKR---------RKSEQDREQEQ 321
            ::..   |:...:.||.         :.||........|||.|.|         |:::....::|
Mouse   696 NDGGTVVNDMSHDNHCH---------SQDEMSPGMSVKDFSKHNRTRCISRTEIRRADSMTSEDQ 751

  Fly   322 EQEQEREREAEKEQ----EQDVESDKEH--------------EPEQEH---------ELEREKRS 359
            |.|::.|.|:|..:    |:.:|.| ||              .|::.|         :::.|...
Mouse   752 EPERDYENESESSEPKLGEESMEGD-EHLHSEVSEKVLMNSERPDENHSEPSHQDVIKVKEEFTD 815

  Fly   360 PS-DAFSMDQLLGKRKRHDSTASSSACSTAAASSASSSSASASANPPQTSIKMDL--DPDSDSAY 421
            |: |.|.|.|.        ...:....|.||...:.:||.: ..:|.:.|.:.||  .||....|
Mouse   816 PTYDMFYMSQY--------GLYNGGGASMAALHESFTSSLN-YGSPQKFSPEGDLCSSPDPKICY 871

  Fly   422 MTSR 425
            :..:
Mouse   872 VCKK 875

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
discoNP_001033847.1 None
Bnc2XP_017175693.1 C2H2 Zn finger 478..499 CDD:275368 13/20 (65%)
C2H2 Zn finger 506..524 CDD:275368 15/17 (88%)
C2H2 Zn finger 1094..1115 CDD:275368
C2H2 Zn finger 1122..1140 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167849215
Domainoid 1 1.000 87 1.000 Domainoid score I8059
eggNOG 1 0.900 - - E1_2C0EZ
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S7987
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0002551
OrthoInspector 1 1.000 - - mtm8901
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR15021
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3798
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
98.870

Return to query results.
Submit another query.