Protein Alignment disco and LOC1282060

DIOPT Version :10

• Sequence 1: NP_523362.2
• Gene: disco / 32579
• FlyBaseID: FBgn0000459
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: XP_061500772.1
• Gene: LOC1282060 / 1282060
• VectorBaseID: AGAMI1_012460
• Length: 1312
• Species: Anopheles gambiae
• Alignment Length: 809
• Identity: 203/809 - (25%)
• Similarity: 283/809 - (34%)
• Gaps: 329/809 - (40%)

  Fly     4 IMNPFMSPAYLLGHGPHSHQHVHSHLPSHPQPNAASPASSPGGSSGSGSGSAAGSGTGSGSSLKP 68
            :..|.:.|...:     |..|   |||.........|.|||...
Mosquito   368 LQQPPLQPGAAM-----SRMH---HLPPSSGGQLKKPPSSPSSK--------------------- 403

  Fly    69 RRWGSPPINLAGQFINPATGKKRVQCSICFKTFCDKGALKIHFSAVHLREMHKCTVEGCNMVFSS 133
            |:||:.|.||..|::|||||||||||::|||||||||||||||||||||||||||||||:|:|||
Mosquito   404 RQWGAIPPNLGTQYVNPATGKKRVQCNVCFKTFCDKGALKIHFSAVHLREMHKCTVEGCSMMFSS 468

  Fly   134 RRSRNRHSANPNPKLHSPHIRRKISPHDGRTAQQFPVFSPGTAAAAAAVAGRLPV-----AFPGL 193
            |||||||||||||||||||:||||||||||:||..|:..  :.|......|..|:     |||
Mosquito   469 RRSRNRHSANPNPKLHSPHLRRKISPHDGRSAQPHPILL--STAGMPLPNGLSPLHPFGPAFP-- 529

  Fly   194 LPPPPPHHGHHPYV------------MFGGQAGLHGLGLLSTGCQDPDSGSVDNEQD-----ADP 241
            |.||..|...||.:            |....|..|....::....:.:|..|....:     :.|
Mosquito   530 LIPPGEHLRGHPSLSALEFKANMEASMHRRLAAEHHHAQVAAEKHNRESARVSLSPENYRYRSSP 594

  Fly   242 EDDNDFVYVDMQA---------NSSSPAASSEDQEEHERD-----------NEQDEEM---HCSL 283
            ..|....|:...:         |||......||.:|.|.|           |:.|:::   ...:
Mosquito   595 HSDTPDRYMGSSSGASSGAPHLNSSGSRLDDEDGDEDEDDDDDRNGIVIDGNDVDDDVEGHQFDM 659

  Fly   284 SLASSSSIAA-------DE----ERAADQPLDFSLHKR--------------------------- 310
            ||:|.|....       ||    ||..::|.||||.||
Mosquito   660 SLSSESEDVKSFGQHEDDEDGFSERGEEEPQDFSLSKRHNRPSTDADDIASNNGDSNGEVTRDDV 724

  Fly   311 ----------RKS---------EQDREQEQEQEQEREREAEKEQE-------------------- 336
                      |||         ...|....|..:|:|..|..|:|
Mosquito   725 NAFLSSNKRKRKSLNPTKCAVVPLSRLSNNEDNEEKEPAARTEEEACETSIPLVKKIKIESIDDD 789

  Fly   337 -------------------------------QDVESDKEHEPEQEHELEREKRSPSDAFSMDQLL 370
                                           |:.:.|||.:....:|:|::          |.|:
Mosquito   790 QPVALLRSEQTVSPGPKSPTEQDSALVSPSLQNGDCDKEGKESNANEIEKD----------DSLV 844

  Fly   371 GKRK--------------------------RHDSTASSSACSTAAASSASSSSASASANPP-QTS 408
            ..|:                          :..|.:.::..|...:...|.||...:||.. |:.
Mosquito   845 SDRRPSGDEEKKVVPNETVRVKAEPTEEGLQEQSASEATDLSLDLSKKQSRSSPDVNANEKFQSK 909

  Fly   409 IKMDLDPDSDSAYMTSRRQMLPLPVLDLEEH---------------------HHLRLLQTQ---- 448
            ..:|:.|.|:   :......|..|..::.|:                     :.||.|:..
Mosquito   910 YSIDVRPSSE---LLENPLSLIRPKQEVSENDRQRPGSADSKKSVGDNFDSANTLRRLENLSHGP 971

  Fly   449 ----MFAAAAAAAATSQAPPTAFLPAGSP------------------------------------ 473
                |...||......|.||.::|...:|
Mosquito   972 LNDIMIQRAAGLLGGPQFPPLSYLMNAAPPSPARSRSPSPPTCQDHELEDSDDNVDYCEEGNCFS 1036

  Fly   474 ---VDLAKDSPPMWSLLSEMYRS-MLLKTQHQQYNHHHQL------------------QQQHQQE 516
               |.|.||:|...|...::::: ..:||.:|  |.|.:|                  :.:|...
Mosquito  1037 DPDVPLDKDNPKKCSACGKLFQNHFAVKTHYQ--NVHLKLLHKCNIDGCNAAFPSKRSRDRHASN 1099

  Fly   517 QHHH--------------LTLSHHHQEQH 531
            .:.|              |.:..|.|:|:
Mosquito  1100 LNLHRKLLSTTADSNETVLPMEKHQQQQY 1128