Protein Alignment disco and Bnc1

DIOPT Version :9

• Sequence 1: NP_001033847.1
• Gene: disco / 32579
• FlyBaseID: FBgn0000459
• Length: 568
• Species: Drosophila melanogaster
• Sequence 2: NP_031588.2
• Gene: Bnc1 / 12173
• MGIID: 1097164
• Length: 990
• Species: Mus musculus
• Alignment Length: 625
• Identity: 158/625 - (25%)
• Similarity: 222/625 - (35%)
• Gaps: 199/625 - (31%)

  Fly    17 HGPHSHQHVHSHLPSHP--------------QPNAASPASSPGGSSGSGSGSAAGSGTGSGSSLK 67
            |||.|..   |.|.|.|              .|.....|.....||.|.:.....:.....:.:|
Mouse   280 HGPFSDS---SFLTSTPFQVEKEQCLNCPETVPQKEDSAHLSDSSSYSIASKLERTQLSPEAKVK 341

  Fly    68 PRRWGSPPINLAGQFINPATGKK-RVQCSICFKTFCDKGALKIHFSAVHLREMHKCTVEGCNMVF 131
            |.|             |..:.|| ||.|:.|.|||.|||.||||::||||:..||||:|||||||
Mouse   342 PER-------------NSLSAKKGRVFCTACEKTFYDKGTLKIHYNAVHLKIKHKCTIEGCNMVF 393

  Fly   132 SSRRSRNRHSANPNPKLHSP--------HIRRKISPHDGRTAQQ--FPVFSP------------- 173
            ||.||||||||||||:||.|        .:|..::.....|.::  |.|.||
Mouse   394 SSLRSRNRHSANPNPRLHMPMNRNNRDKDLRNSLNLASSETYKRPGFTVVSPDCGPLPGYTGSVE 458

  Fly   174 -GTAAAAAAVAGRLPVAFPGL-----------LPPPPPHHGHHPYVMFGGQAGLHGLGLLSTGCQ 226
             .....|.:..|:..|.||.|           .|..|....:.|.:       |..|.|||:...
Mouse   459 DSKGQPAFSSIGQNGVLFPNLKTVQPVLPFYRSPATPAELANTPGM-------LPSLPLLSSSIP 516

  Fly   227 DPDSGSVDNEQDADPED-----------DNDFVYV------DMQANSSSP-AASSEDQEEHE--R 271
            : ...|.|...||.|:.           :.:.|.:      .:.::...| ...|||:.|..  |
Mouse   517 E-QLVSTDMPFDALPKKKSRKSSMPIKIEKEAVEIAEEKRHSLSSDDEVPLQVVSEDEPEDSSPR 580

  Fly   272 DNEQDEEMHCSLSLASSSSIAADEERA--------ADQPLDFSLHKRRKSEQDREQEQEQEQERE 328
            .:...||.|..|||...   ....|||        :...|..:|.:...:|::.||:........
Mouse   581 SDRVPEEQHTQLSLEEP---LPQGERACHLESVIESHGALSRTLEQTTLTEREAEQKVALSSVMP 642

  Fly   329 REAE---------------------KEQEQD-------------------VESDKEHEPEQEHEL 353
            ||.|                     .|.:|.                   :|..||.|...||.|
Mouse   643 REVEDGGHERHFTAGLVPQIPFPDYMELQQRLLAGGLFGALSNRGMAFPFLEESKELEHLGEHAL 707

  Fly   354 ERE-----------KRSPSDAFSMDQLLGKRKRHDSTA---SSSACSTAAASSASSSSASASANP 404
            .|:           |::..:|.||       |.|:...   .:.||:.....:|..|..|.
Mouse   708 VRQKEEACFQCDICKKTFKNACSM-------KTHEKNTHARETHACTVEGCGAAFPSRRSR---- 761

  Fly   405 PQTSIKMDLDPDSDSAYMTSRRQMLPLPVLDLEEHHH--LRLLQTQMFAAAAAAAATSQAPPTAF 467
                       |..|:.::..:::|....|:..|.|.  ..|||.....|....|.|.||..|:.
Mouse   762 -----------DRHSSNLSLHQKVLNEEALETSEDHFRAAYLLQDVAKEAYQDVAFTPQASQTSV 815

  Fly   468 LPAGSPVDLAKDSPPMWSL---LSEMYRSMLLKTQHQQYN 504
                    :.|.:..|.||   :|:::.:.|     :.||
Mouse   816 --------IFKGTSGMGSLVYPISQVHSASL-----ESYN 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
disco	NP_001033847.1	None
Bnc1	NP_031588.2	C2H2 Zn finger	356..377	CDD:275368	13/20 (65%)
		C2H2 Zn finger	384..402	CDD:275368	15/17 (88%)
		C2H2 Zn finger	718..739	CDD:275368	6/27 (22%)
		C2H2 Zn finger	746..774	CDD:275368	6/42 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849214
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2C0EZ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D59377at33208
OrthoFinder	1	1.000	-	-		FOG0002551
OrthoInspector	1	1.000	-	-		mtm8901
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15021
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3798
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.930