DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8958 and egl-4

DIOPT Version :9

Sequence 1:	NP_573105.1	Gene:	CG8958 / 32575	FlyBaseID:	FBgn0030725	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_001294450.1	Gene:	egl-4 / 176991	WormBaseID:	WBGene00001173	Length:	783	Species:	Caenorhabditis elegans

Alignment Length:	286	Identity:	54/286 - (18%)
Similarity:	109/286 - (38%)	Gaps:	94/286 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 KNVALMRQ----KRKPGML-----TVADKALLRSNPAYRTIEERKKLC--ILIAGLNCFSRIPPK 103
            |.:|:..:    :.||..|     ||..|.::|.  |.:..:..|:|.  .:|..:||..    :
Worm   161 KKIAVSAEPTNFENKPATLQHYNKTVGAKQMIRD--AVQKNDFLKQLAKEQIIELVNCMY----E 219

  Fly   104 IRARMVPVLKFMSINEPRVIIKNGDMPISVYFILNGEVEMKKNTNNKAVKLEDAVAEAIFG---P 165
            :|||           ..:.:|:.|:....::.:..||:::.:.             .|:.|   .
Worm   220 MRAR-----------AGQWVIQEGEPGDRLFVVAEGELQVSRE-------------GALLGKMRA 260

  Fly   166 GDCFGDVEMVEECPRMNTYLALSSCEV----LSIYDIDYER------------ILKPHMLKQWNE 214
            |...|::.::..|.|..:..||:..::    .|::.:..:|            :.|..:.:..:|
Worm   261 GTVMGELAILYNCTRTASVQALTDVQLWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSE 325

  Fly   215 KKLALKA----FDYFDFLTPDQIILACKYSYLVQYEPLETIYMGDTDSLGYVRFVL-SGECVILQ 274
            .:::..|    .||:|           ...|:::        .|:....|...||: ||:
Worm   326 DRISKMADVMDQDYYD-----------GGHYIIR--------QGEKCLQGDAFFVINSGQ----- 366

  Fly   275 CLSMKVT-NTEGEVN-YELTEINKDD 298
               :||| ..|||.. .|:..:|:.|
Worm   367 ---VKVTQQIEGETEPREIRVLNQGD 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8958	NP_573105.1	Crp	97..>212	CDD:223736	18/133 (14%)
CG8958	NP_573105.1	CAP_ED	97..207	CDD:237999	18/128 (14%)
egl-4	NP_001294450.1	Crp	195..>316	CDD:223736	23/148 (16%)
		CAP_ED	201..314	CDD:237999	22/140 (16%)
		Crp	313..>427	CDD:223736	22/104 (21%)
		CAP_ED	319..437	CDD:237999	21/98 (21%)
		PTZ00263	461..779	CDD:140289
		STKc_cGK	478..739	CDD:270724
		S_TK_X	734..783	CDD:214529
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910