Protein Alignment CG8958 and CNBD2

DIOPT Version :10

• Sequence 1: NP_573105.1
• Gene: CG8958 / 32575
• FlyBaseID: FBgn0030725
• Length: 621
• Species: Drosophila melanogaster
• Sequence 2: XP_047295877.1
• Gene: CNBD2 / 140894
• HGNCID: 16145
• Length: 635
• Species: Homo sapiens
• Alignment Length: 605
• Identity: 101/605 - (16%)
• Similarity: 201/605 - (33%)
• Gaps: 212/605 - (35%)

  Fly    71 LLRSNPAYRTIEERKKLCILIAGLNCFSRIPPKIRARMVPVLKFMSINEPRVIIKNGDMPISVYF 135
            :::..|::||.:|.:.:|.::..|:.:......::..:..|::|......|||||.|....|.||
Human   150 IMQKKPSWRTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYF 214

  Fly   136 ILNGEVEMKKNTNNKAVKLEDAVAEAIFGPGDCFGDVEMVEECPRMNTYLALSSCEVLSIYDID- 199
            |..|.|.:.|:.:..:..|:.  ...:...|.|||:::::....|.:|.:.:...|.|.:...|
Human   215 IYLGTVAITKDEDGSSAFLDP--HPKLLHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDF 277

  Fly   200 ----------------YERILKPHMLKQWNEKKL-------ALKAFDYFDFLTPDQIILACKYSY 241
                            :|...|..:...|:::||       .::.|.|...::.|
Human   278 FANKLDQEVQKDAQYRFEFFRKMELFASWSDEKLWQLVAMAKIERFSYGQLISKD---------- 332

  Fly   242 LVQYEPLETIYMGDTDSLGYVRFVLSGECVILQCLSMKVTNTEGEVNYELTEINKDDGLEMFQSW 306
                       .|::.   ::.|:..|.|.:|:.|.:..:.:.....::..|:  .||..:....
Human   333 -----------FGESP---FIMFISKGSCEVLRLLDLGASPSYRRWIWQHLEL--IDGRPLKTHL 381

  Fly   307 KDVTSRNSFLDIQDILASSTSSEEVEGGTKKKQAMRKMGLAEIQKFCGLRTSNTPSRK-----KT 366
            .:.:....|             :|.:..:...|....:.|..::|..||:.::. |||     .|
Human   382 SEYSPMERF-------------KEFQIKSYPLQDFSSLKLPHLKKAWGLQGTSF-SRKIRTSGDT 432

  Fly   367 KPRRTLSTAAQARKTQLIQSLRRGTPWMPSVMPNDDDDDDDDDDGHIDEDYMGYGEDLYDEVDTD 431
            .| :.|....|:|..|.|:
Human   433 LP-KMLGPKIQSRPAQSIK---------------------------------------------- 450

  Fly   432 DSSYDSNSSSSSVSMDRTLVQVQLKPHSAGSSPSEKKVSSSSSEIFTASSVINEKSLVDESPKPI 496
                              ...:.:||   |..|.|..|.:
Human   451 ------------------CAMINIKP---GELPKEAAVGA------------------------- 469

  Fly   497 KEPVETHFIDVGSLTYGSVFGLGEKMEHRVIMARTVVQCLLLPRFWLLEEEQNPGN--IWHRRRF 559
                   ::.|.::..|.:.||     |:..:...  :|...|...:     :.||  |..|:..
Human   470 -------YVKVHTVEQGEILGL-----HQAFLPEG--ECDTRPLILM-----SLGNELIRIRKEI 515

  Fly   560 YFE--------------CNV--PSRQDLFTNFLKTRQWNKFRHDYIESLLD----------REEK 598
            ::|              .|:  ||.:|:...||:...||.||.|.::.|::          |.:|
Human   516 FYELIDNDDEMIKKLLKLNIAFPSDEDMCQKFLQQNSWNIFRKDLLQLLVEPCQSQLFTPNRPKK 580

  Fly   599 GNITKEEDIPI-MCRIVETS 617
            ..|...:.:.: :|.|.:|:
Human   581 REIYNPKSVVLDLCSINKTT 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8958	NP_573105.1	CAP_ED	97..207	CDD:237999	27/126 (21%)
CNBD2	XP_047295877.1	CAP_ED	181..277	CDD:237999	24/97 (25%)