Protein Alignment Tob and Tob2

DIOPT Version :9

• Sequence 1: NP_001162772.1
• Gene: Tob / 32574
• FlyBaseID: FBgn0028397
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_065253.1
• Gene: Tob2 / 57259
• MGIID: 1888525
• Length: 345
• Species: Mus musculus
• Alignment Length: 446
• Identity: 146/446 - (32%)
• Similarity: 201/446 - (45%)
• Gaps: 133/446 - (29%)

  Fly     1 MHIEIQVALNFVISYLYNKLPRRRVNIFGEELEKALRDKFQDHWYPEKPFKGSAYRCLKTGDPID 65
            |.:||:|||||:||||||||||||.::||||||:.||.|::.|||||||.|||.:||:..|:.:|
Mouse     1 MQLEIKVALNFIISYLYNKLPRRRADLFGEELERLLRKKYEGHWYPEKPLKGSGFRCVHIGEVVD 65

  Fly    66 SVLERAARESGVPIGDILENLPNELSVWIDPGEVSFRIGEKGAVKILYTENNENHEDSHSADREV 130
            .|:|.||:.||:.:.|:..|:|.||||||||.|||::|||||.||:||..::| ...:...|:|:
Mouse    66 PVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGVVKVLYLGDSE-ASGTPELDKEI 129

  Fly   131 TKMFNPEAQCFRPIDAVNTTMNNMSLSPKGHHQSGSSPHSAASSSPTYKGSPNRTISGSCSSVSG 195
            ...|||:||.|.||                     .|..|:.||||
Mouse   130 KSSFNPDAQVFVPI---------------------GSQDSSLSSSP------------------- 154

  Fly   196 AGSGTGSGSRSGSNHAPGPGTAPGPVPGNGATANAAAAAFMQRGAQAPLTFTTATFAQTKFGSTK 260
                           :|..|.:|.|             .|:.|.|| |:|||||:||.|||||||
Mouse   155 ---------------SPSFGQSPSP-------------TFIPRSAQ-PITFTTASFAATKFGSTK 190

  Fly   261 LKTSSKRTNSSSA--------------YRMSPTEFSNYIKQRAMQQQMHHGHAVVPSAGSSVSAA 311
            :|.....:...|.              .||:.:...|.:|.:::...||..:.:..:.
Mouse   191 MKKGGGASGGVSVGGSGAGGQQPPPQQPRMARSPTKNLLKHKSLSLSMHSLNLIPANP------- 248

  Fly   312 YGGMDAVSPARSLSPNPLSLAGNQNQSVSGSSADSYYYPNMPINMYPQYGNPRCLFESHFSADVS 376
                   :|...||||....                        :|...|:|...|:.......|
Mouse   249 -------APQSQLSPNAKEF------------------------VYNGGGSPSLFFDGVEGPSTS 282

  Fly   377 SMGLYVSGTAGAA------VTAVGSVGANKYSTYLEPCYYGNG---HANTQQHSQQ 423
            :...:.||.|...      |:.|...|||  |.:||...:..|   :.||.|:..|
Mouse   283 TTAPFGSGGASTCNSSSFDVSQVFGGGAN--SLFLEKSPFVEGLSYNLNTMQYPNQ 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tob	NP_001162772.1	BTG	1..112	CDD:285041	70/110 (64%)
Tob2	NP_065253.1	BTG	1..106	CDD:417713	65/104 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..170		11/72 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..225		7/36 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837833
Domainoid	1	1.000	168	1.000	Domainoid score	I3822
eggNOG	1	0.900	-	-		E1_KOG4006
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	199	1.000	Inparanoid score	I3781
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000571
OrthoInspector	1	1.000	-	-		otm43544
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR17537
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5717
SonicParanoid	1	1.000	-	-		X3071
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.880