DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nipsnap and Nipsnap1

DIOPT Version :9

Sequence 1:	NP_001285316.1	Gene:	Nipsnap / 32573	FlyBaseID:	FBgn0030724	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001094200.1	Gene:	Nipsnap1 / 360971	RGDID:	1310419	Length:	284	Species:	Rattus norvegicus

Alignment Length:	264	Identity:	132/264 - (50%)
Similarity:	166/264 - (62%)	Gaps:	17/264 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 AVRSLSTTPSRNDSE-SWFSKLLVRKIEPTKESHSRMLSDKEI--IYALHTHNVRPDSMGSYLNN 78
            |||..|     .||| |||..|.|.|::|.|::||.:||.||.  :|.:..|||:|:.:.:|  |
  Rat    31 AVRFYS-----KDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPECLDAY--N 88

  Fly    79 YKTTVALINEKKANLS----CELVASWTVQVGDMDQCLHLWKYTGGFEKIDQAKEDLWNDPEYLS 139
            ..|...|   .|.:|.    |.||.:|....|:.||.:|||:::||:..:......|..:.|||.
  Rat    89 SLTEAVL---PKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKTNKEYLE 150

  Fly   140 LMQERSKFLRSRHLQYLLAFSYWPQIASRTGKNIYEMRSYRLTPGTMIEWGNNWARAINYRKHNN 204
            ..:||||.|.||..|.||.||:|.:...|.|.||||:|:|:|.|||||||||||||||.||:.|.
  Rat   151 FRKERSKMLLSRRNQLLLEFSFWNEPQPRAGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQ 215

  Fly   205 EAFAGFFSQIGRLYNVHHIWCYKSLQDRKETREAAWRSPGWDECVAYTVPLIREMHCRVLAPTEF 269
            ||..|||||||.||.|||:|.||.||.|:|||.||||..||||.|.|||||:|.|..|::.|.:.
  Rat   216 EAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKI 280

  Fly   270 SPSQ 273
            ||.|
  Rat   281 SPLQ 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nipsnap	NP_001285316.1	NIPSNAP	174..271	CDD:285252	64/96 (67%)
Nipsnap1	NP_001094200.1	NIPSNAP	185..282	CDD:400368	64/96 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341893
Domainoid	1	1.000	152	1.000	Domainoid score	I4228
eggNOG	1	0.900	-	-		E1_KOG2883
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	260	1.000	Inparanoid score	I3035
OMA	1	1.010	-	-		QHG52951
OrthoDB	1	1.010	-	-		D1141024at2759
OrthoFinder	1	1.000	-	-		FOG0003040
OrthoInspector	1	1.000	-	-		otm46142
orthoMCL	1	0.900	-	-		OOG6_103770
Panther	1	1.100	-	-	LDO	PTHR21017
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1761
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810