DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nipsnap and nipsnap2

DIOPT Version :9

Sequence 1:	NP_001285316.1	Gene:	Nipsnap / 32573	FlyBaseID:	FBgn0030724	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_571109.1	Gene:	nipsnap2 / 30232	ZFINID:	ZDB-GENE-991008-18	Length:	286	Species:	Danio rerio

Alignment Length:	266	Identity:	132/266 - (49%)
Similarity:	173/266 - (65%)	Gaps:	4/266 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 AVGKSNNNAV-RSLSTTPSRNDSESWFSKLLVRKIEPTKESHSRMLSDKE--IIYALHTHNVRPD 70
            |.||.:..|| ||||.:.:|...:|||..|.|||::|.|::||.:|:.||  .:|.:..|||:|:
Zfish    20 ARGKGHATAVIRSLSASHNRPREDSWFKSLFVRKVDPRKDAHSHLLAKKEDNNLYKIQFHNVKPE 84

  Fly    71 SMGSYLNNYKTTVALINEKKANLSCELVASWTVQVGDMDQCLHLWKYTGGFEKIDQAKEDLWNDP 135
            .:.:|....:..:..|:..|| ..||||.:|....|:.||.:|||:|.||:..:.:....|.|:.
Zfish    85 CLEAYNKLCEDVLTNIHTDKA-YPCELVGTWNTWYGEQDQAVHLWRYRGGYPALTEVMSKLKNNK 148

  Fly   136 EYLSLMQERSKFLRSRHLQYLLAFSYWPQIASRTGKNIYEMRSYRLTPGTMIEWGNNWARAINYR 200
            |:|....||.|.|.||..|.||.||:|.:...|.|.||||:|||:|.|||||||||.|||||.||
Zfish   149 EFLEYRSERGKMLLSRRNQLLLEFSFWNEPVPRDGPNIYELRSYQLRPGTMIEWGNYWARAIGYR 213

  Fly   201 KHNNEAFAGFFSQIGRLYNVHHIWCYKSLQDRKETREAAWRSPGWDECVAYTVPLIREMHCRVLA 265
            :||.||..|||||||.||.|||:|.||.||.|::||.|||:..||||.|.||||||:.|..|::.
Zfish   214 QHNREAVGGFFSQIGDLYMVHHLWAYKDLQSREDTRNAAWQHEGWDEVVYYTVPLIQHMESRIMI 278

  Fly   266 PTEFSP 271
            |.:.||
Zfish   279 PLKNSP 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nipsnap	NP_001285316.1	NIPSNAP	174..271	CDD:285252	63/96 (66%)
nipsnap2	NP_571109.1	NIPSNAP	187..284	CDD:285252	63/96 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	148	1.000	Domainoid score	I4420
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1137
Inparanoid	1	1.050	270	1.000	Inparanoid score	I2982
OMA	1	1.010	-	-		QHG52951
OrthoDB	1	1.010	-	-		D1141024at2759
OrthoFinder	1	1.000	-	-		FOG0003040
OrthoInspector	1	1.000	-	-		otm25463
orthoMCL	1	0.900	-	-		OOG6_103770
Panther	1	1.100	-	-	O	PTHR21017
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R944
SonicParanoid	1	1.000	-	-		X1761
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	14.010