DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nipsnap and C45E5.1

DIOPT Version :9

Sequence 1:	NP_001285316.1	Gene:	Nipsnap / 32573	FlyBaseID:	FBgn0030724	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_500857.2	Gene:	C45E5.1 / 183469	WormBaseID:	WBGene00016664	Length:	303	Species:	Caenorhabditis elegans

Alignment Length:	149	Identity:	27/149 - (18%)
Similarity:	56/149 - (37%)	Gaps:	37/149 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SNNNAVRSLSTTPSRNDSESWFSKLLVRKIEPTKESHSRMLSDKEIIYALHTHNVRPDSMGSYLN 77
            :.||:.::|         |.:..|  |:|:...:.....:||...::......|     ...:.|
Worm    54 TTNNSTKTL---------EQYMKK--VKKMRFGRLGRENLLSPTIVLCDYFKQN-----SDKFEN 102

  Fly    78 NYKTTVALINEKKANLSCELVASWTVQVGDMDQCLHLWKYTGGFEKIDQAKEDLWNDPEYLSLMQ 142
            .|...:.:.|.||           :::.|...:|..    ||...|      |.:.|.::::.:.
Worm   103 QYIYLIGVENLKK-----------SLEEGGGVKCFG----TGPDHK------DNYTDGDFINEVD 146

  Fly   143 ERSKFLRSRHLQYLLAFSY 161
            .:||..::..:.:...|||
Worm   147 VKSKIPKAVVVSFDSHFSY 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nipsnap	NP_001285316.1	NIPSNAP	174..271	CDD:285252
C45E5.1	NP_500857.2	HAD-SF-IIA	18..274	CDD:273637	27/149 (18%)
		Hydrolase_6	18..121	CDD:290083	15/93 (16%)
		Hydrolase_like	221..284	CDD:289983
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103770
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1761
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810