DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nipsnap and Nipsnap1

DIOPT Version :9

Sequence 1:	NP_001285316.1	Gene:	Nipsnap / 32573	FlyBaseID:	FBgn0030724	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	XP_006514638.1	Gene:	Nipsnap1 / 18082	MGIID:	1278344	Length:	287	Species:	Mus musculus

Alignment Length:	254	Identity:	127/254 - (50%)
Similarity:	163/254 - (64%)	Gaps:	11/254 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SRNDSESWFSKLLVRKIEPTKESHSRMLSDKEI--IYALHTHNVRPDSMGSYLNNYKTTVALINE 88
            |::...|||..|.|.|::|.|::||.:||.||.  :|.:..|||:|:.:.:|  |..|...|
Mouse    39 SKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPECLDAY--NSLTEAVL--- 98

  Fly    89 KKANLS----CELVASWTVQVGDMDQCLHLWKYTGGFEKIDQAKEDLWNDPEYLSLMQERSKFLR 149
            .|.:|.    |.||.:|....|:.||.:|||:::||:..:......|.|:.|||...:||||.|.
Mouse    99 PKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRKERSKMLL 163

  Fly   150 SRHLQYLLAFSYWPQIASRTGKNIYEMRSYRLTPGTMIEWGNNWARAINYRKHNNEAFAGFFSQI 214
            ||..|.||.||:|.:...|.|.||||:|:|:|.|||||||||||||||.||:.|.||..||||||
Mouse   164 SRRNQLLLEFSFWNEPQPRAGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQI 228

  Fly   215 GRLYNVHHIWCYKSLQDRKETREAAWRSPGWDECVAYTVPLIREMHCRVLAPTEFSPSQ 273
            |.||.|||:|.||.||.|:|||.||||..||||.|.|||||:|.|..|::.|.:.||.|
Mouse   229 GELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nipsnap	NP_001285316.1	NIPSNAP	174..271	CDD:285252	64/96 (67%)
Nipsnap1	XP_006514638.1	NIPSNAP	188..285	CDD:311781	64/96 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838113
Domainoid	1	1.000	152	1.000	Domainoid score	I4310
eggNOG	1	0.900	-	-		E1_KOG2883
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	263	1.000	Inparanoid score	I3069
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52951
OrthoDB	1	1.010	-	-		D1141024at2759
OrthoFinder	1	1.000	-	-		FOG0003040
OrthoInspector	1	1.000	-	-		otm44053
orthoMCL	1	0.900	-	-		OOG6_103770
Panther	1	1.100	-	-	LDO	PTHR21017
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R944
SonicParanoid	1	1.000	-	-		X1761
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.800