DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr18 and Igsf9

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001139272.1	Gene:	Igsf9 / 93842	MGIID:	2135283	Length:	1179	Species:	Mus musculus

Alignment Length:	340	Identity:	66/340 - (19%)
Similarity:	97/340 - (28%)	Gaps:	150/340 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 FFEEPINSATSGDNLVSAVHLFTEAVL-------------NCRVGMLKDKTV-------MWVRRT 262
            |.:..:.|.....:.|..|.|.|.|.|             .|||..|...:.       .||..|
Mouse    67 FIQFGLYSPRIDPDYVGRVRLQTGASLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVHLT 131

  Fly   263 A-------------------EKVSLLTVGNVTYSGDPRIRVKFQY-------------PNNWRLL 295
            .                   |.|:|..|..    |.|:..|.:::             ..|..|.
Mouse   132 VNSPPQFQETPPLVLEVKELEAVTLRCVAR----GSPQPYVTWKFRGQDLGKGQGQVQVQNGTLW 192

  Fly   296 INPTQTEDAGVYMCQVS------THPPRVFTTNLTVLEPPLRIIDEHERDVGDRYYKSGSTVDLQ 354
            |...:...||.|.||.|      ||     .|.|.||.||:.::......|     .|...|.|.
Mouse   193 IRRVERGSAGDYTCQASSSEGSITH-----ATQLLVLGPPVIVVPPSNSTV-----NSSQDVSLA 247

  Fly   355 CQ-------ISRSFFQKERQTILKSTDSANDAVQKLINETTSELNLIGNVNQTQHKFSGQDLEKY 412
            |:       ::.|:||          |..|                :.::::.|.:.
Mouse   248 CRAEAYPANLTYSWFQ----------DGVN----------------VFHISRLQSRV-------- 278

  Fly   413 FTKFITWAKDEEPLQGMTNRRLSVSDVWLTSRISIGDAKLSDSGNYSC----------SLGRLFT 467
                               |.|....:||.:      .:..|:|:|:|          |.....|
Mouse   279 -------------------RILVDGSLWLQA------TQPDDAGHYTCVPSNGFLHPPSASAYLT 318

  Fly   468 VI--VQVQVLTGELP 480
            |:  .||.|:..|.|
Mouse   319 VLYPAQVTVMPPETP 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	29/140 (21%)
		Ig	<258..326	CDD:299845	23/105 (22%)
		IGc2	<417..461	CDD:197706	8/53 (15%)
Igsf9	NP_001139272.1	IG_like	28..110	CDD:214653	9/42 (21%)
		Ig	136..223	CDD:386229	20/95 (21%)
		Ig_3	227..305	CDD:372822	20/141 (14%)
		Ig	341..404	CDD:386229
		Ig	436..500	CDD:319273
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	767..807
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..842
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..974
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1016..1079
		PDZ-binding	1177..1179
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900