DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr18 and DIP-delta

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001097508.2	Gene:	DIP-delta / 5740816	FlyBaseID:	FBgn0085420	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	298	Identity:	66/298 - (22%)
Similarity:	111/298 - (37%)	Gaps:	67/298 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 PFFEEPINSATSGDNLVSAVHLFTEAVLNCRVGMLKDKTVMWVRRTAEKVSLLTVGNVTYSGDPR 281
            |.|.:||.:.|        |.:..:|.|.|.|..|....|.|:.  .::..:||:.....|..||
  Fly    44 PRFAQPIPNVT--------VAVGRDANLPCVVEHLGGYKVAWIH--IDRQMILTIHRHVISRIPR 98

  Fly   282 IRVKFQYPNNWRLLINPTQTEDAGVYMCQVSTHPPRVFTTNLTVLEPPLRIIDEHERDVGDRYYK 346
            ..:.:. .|.|.|.:|....:|.|.|||||:|:|.......|.|:.|| .|:| .|........:
  Fly    99 YSITYT-DNTWLLHVNQAHQDDRGYYMCQVNTNPMISQVGYLQVVVPP-NILD-IESTPSSVAVR 160

  Fly   347 SGSTVDLQCQI---------------SRSFFQKERQTILKSTD-------SAND----------- 378
            ....:::.|:.               .....:|:::.::...|       |.|:
  Fly   161 ENQNINMTCRADGFPAPKIIWRREDGEEIAVEKKKKVLVYDADVLPLTKVSRNEMGAYLCIATNG 225

  Fly   379 ---AVQKLINETTSELNLIGNVNQTQHKFSGQDL------EKYFTKFITWAKDEEPLQGMTNRRL 434
               :|.|.|........:|...||.....||.|:      |.:....|.|..:.  :..:.:::.
  Fly   226 VPPSVSKRIILDVEFSPMIWVPNQLVGAPSGTDVTIDCHTEAHPKAIIYWVYNS--VMVLPSKKY 288

  Fly   435 SVSDVWLTS-----RISIGDAKLSDSGNYSC----SLG 463
            . :|....|     :::|.:.:..|.|||.|    |||
  Fly   289 K-TDYTENSYRAHMKLTIRNLQYGDFGNYRCISKNSLG 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	26/82 (32%)
		Ig	<258..326	CDD:299845	20/67 (30%)
		IGc2	<417..461	CDD:197706	10/52 (19%)
DIP-delta	NP_001097508.2	IG	51..143	CDD:214652	29/102 (28%)
		Ig	145..238	CDD:416386	12/94 (13%)
		Ig strand A	145..149	CDD:409353	2/4 (50%)
		Ig strand A'	154..159	CDD:409353	0/4 (0%)
		Ig strand B	165..172	CDD:409353	1/6 (17%)
		Ig strand C	178..183	CDD:409353	0/4 (0%)
		Ig strand C'	185..187	CDD:409353	0/1 (0%)
		Ig strand D	195..199	CDD:409353	0/3 (0%)
		Ig strand E	203..209	CDD:409353	1/5 (20%)
		Ig strand F	216..223	CDD:409353	0/6 (0%)
		Ig strand G	230..238	CDD:409353	3/7 (43%)
		Ig	242..333	CDD:416386	20/87 (23%)
		Ig strand A'	250..253	CDD:409353	0/2 (0%)
		Ig strand B	259..266	CDD:409353	0/6 (0%)
		Ig strand C	272..277	CDD:409353	2/4 (50%)
		Ig strand C'	281..283	CDD:409353	0/1 (0%)
		Ig strand D	289..293	CDD:409353	1/4 (25%)
		Ig strand E	295..305	CDD:409353	1/9 (11%)
		Ig strand F	314..322	CDD:409353	4/7 (57%)
		Ig strand G	325..334	CDD:409353	1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810