DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr18 and igsf9ba

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	XP_009289969.2	Gene:	igsf9ba / 567389	ZFINID:	ZDB-GENE-060503-729	Length:	1475	Species:	Danio rerio

Alignment Length:	363	Identity:	69/363 - (19%)
Similarity:	109/363 - (30%)	Gaps:	148/363 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 TVTMPTTAFASLKVDRSTMKQPIDSTRTRNHWTASG---FARVTERPRSKH----HHE-----HH 214
            ::|:..|||.:.|...:.:::....|.||.:..:.|   ...:|...|..:    |.:     |.
Zfish   156 SITLTCTAFGNPKPVVTWLREGDQLTSTRKYTVSDGSLTVQAITREDRGAYSCRAHSDQGEALHT 220

  Fly   215 WGPFFEEPINSATSGDNLVSAVHLFTEAVLNCRV----GMLKDKTVMWVRRTAEKVSLLTVGNVT 275
            .....:.|....|..:|:  .|::...|...|:.    |.|   |..|....         .||.
Zfish   221 TRLLVQGPPYIVTPPENI--TVNISQNAQFTCQAEAYPGNL---TYTWYWEE---------DNVY 271

  Fly   276 YSGDPRIRVKFQYPNNWRLLINPTQTEDAGVYMCQVST---------------HPPRVFTTNLTV 325
            :..|.::||:......  |:|...:.||||.|.|..|.               :|.||      |
Zfish   272 FKNDLKLRVRIFIDGT--LIIYRVKPEDAGKYTCSPSNSLGISPSASAYLTVQYPARV------V 328

  Fly   326 LEPPLRIIDEHERDVGDRYYKSGSTVDLQCQISRSFFQKERQTILKSTDSANDAVQKLINETTSE 390
            ..||:                             .:..::...|::....||..|       ||
Zfish   329 NMPPV-----------------------------IYVPRKLSGIIRCPVDANPPV-------TS- 356

  Fly   391 LNLIGNVNQTQHKFSGQDLEKYFTKFITWAKDEEPLQ--------GMTNRRLSVSDVWLTSRISI 447
                                      :.|.||..||:        .||:..:.|::|
Zfish   357 --------------------------VRWEKDGYPLRIEKYPGWSQMTDGSIRVAEV-------- 387

  Fly   448 GDAKLSDS-GNYSCSLGRLFTVIVQVQVL--TGELPAA 482
                ..|| |.|:|         |...||  .|:.|.|
Zfish   388 ----TEDSLGTYTC---------VPYNVLGTMGQSPPA 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	23/101 (23%)
		Ig	<258..326	CDD:299845	18/82 (22%)
		IGc2	<417..461	CDD:197706	13/52 (25%)
igsf9ba	XP_009289969.2	IG	30..115	CDD:214652
		I-set	139..225	CDD:254352	13/68 (19%)
		I-set	229..321	CDD:333254	23/107 (21%)
		Ig	345..415	CDD:325142	25/123 (20%)
		Ig	438..503	CDD:319273
		FN3	511..606	CDD:238020
		FN3	622..706	CDD:238020
		Atrophin-1	<924..1361	CDD:331285
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810