DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr18 and paplna

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	XP_005169942.1	Gene:	paplna / 562930	ZFINID:	ZDB-GENE-070815-4	Length:	1187	Species:	Danio rerio

Alignment Length:	392	Identity:	81/392 - (20%)
Similarity:	141/392 - (35%)	Gaps:	97/392 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KGYRTLSPASNAAQ--TLPLSYNSQ-TSLSLLRLLTIALVIGSQVQVLYTTSVETKS-------- 58
            :..|...|||||.|  ....|:.:: .|:......|:..::|.:|.:....:....|
Zfish   806 RAQRAHQPASNAMQQSNPAASWTAEGVSIDKTDPSTVEGLVGQRVVLPCRVTPPPSSAVLVEWRR 870

  Fly    59 ------PSASEQSRNGENRSLLFDDYNKTKSTLSTADYLSATRATLYAFSSQDQDEDHSQMPIEA 117
                  |:..||..:|   |||....     ||..:.:       ....:::|...||..:.:..
Zfish   871 DGVPVDPTRHEQQLDG---SLLVGPI-----TLQDSGW-------FLCVATRDDKRDHRYIYLSV 920

  Fly   118 S-----NAPHSPIPTKMSRGKIPMETPGSMEFSSNSLPI--KNVGTTDQLTTVTMPTTAFASLKV 175
            |     ||..|.:.:..|     ..:..|..|:.:..|:  ...|.|.:|....:|.:|..::.:
Zfish   921 SGSSQNNAGISEVDSSQS-----YTSQSSSRFNIDYSPLVEARAGQTAKLQCSVLPVSAIHAVTI 980

  Fly   176 DRSTMKQPIDSTRTRNHWTASGFARVTERPRSKHHHEHHWGPFFEEPINSATSG--DNLVSAVHL 238
            ..|...||::|.|                     |.:|..|....:.:.:..||  ...|:....
Zfish   981 HWSRAGQPLNSLR---------------------HSQHSDGTLVIKQLTADDSGLYTCTVTDAQK 1024

  Fly   239 FTEAVLNCRV-GMLK------DKTVMWVRRTAEKVSLLTVGNV----TYSGDP------RIRVKF 286
            |.|..:..|| |.|:      |..|: ...||:...::|..||    :.:|.|      |:.|.
Zfish  1025 FEERQVQLRVLGDLRITKAPIDVDVV-QGSTAQLACVVTGENVNVGWSRNGVPVRPDGHRVHVS- 1087

  Fly   287 QYPNNWRLLINPTQTEDAGVYMCQVSTHPPRVFTTNLTV-LEPPLRIIDEHERDVGDRYYKSGST 350
               .:..|::|..|:.|.|.|.|       ..:|..|:| ....:|:....::|:....:.|...
Zfish  1088 ---ADGTLILNNVQSVDEGTYTC-------NAYTGTLSVSAAAEIRLAKTPQQDIDGGQFSSSDC 1142

  Fly   351 VD 352
            ||
Zfish  1143 VD 1144

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	24/99 (24%)
		Ig	<258..326	CDD:299845	19/78 (24%)
		IGc2	<417..461	CDD:197706
paplna	XP_005169942.1	TSP1	24..75	CDD:214559
		ADAM_spacer1	181..293	CDD:310520
		TSP1	303..356	CDD:214559
		TSP1	388..442	CDD:214559
		TSP1	449..498	CDD:214559
		TSP1	504..557	CDD:214559
		KU	720..771	CDD:238057
		Ig_3	839..906	CDD:316449	13/81 (16%)
		IGc2	960..1022	CDD:197706	16/82 (20%)
		I-set	1039..1121	CDD:333254	21/93 (23%)
		PLAC	1142..1173	CDD:312271	2/3 (67%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900