DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr18 and NTM

DIOPT Version :9

Sequence 1:NP_573102.1 Gene:dpr18 / 32572 FlyBaseID:FBgn0030723 Length:519 Species:Drosophila melanogaster
Sequence 2:NP_001338930.1 Gene:NTM / 50863 HGNCID:17941 Length:367 Species:Homo sapiens


Alignment Length:319 Identity:65/319 - (20%)
Similarity:113/319 - (35%) Gaps:96/319 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   208 KHHHEHHWGPF--------FE-EPINSATSG-----DNLVSAVHLFTEAVLNCRVGMLKDKTVMW 258
            |.|:...|..|        |: .|:.|..:.     ||:  .|.....|.|.|.:.. :...|.|
Human     7 KMHNSISWAIFTGLAALCLFQGVPVRSGDATFPKAMDNV--TVRQGESATLRCTIDN-RVTRVAW 68

  Fly   259 VRRTAEKVSLLTVGNVTYSGDPRIRVKFQYPNNWRLLINPTQTE-----------DAGVYMCQVS 312
            :.|:    ::|..||..:..|||:           :|::.|||:           |.|.|.|.|.
Human    69 LNRS----TILYAGNDKWCLDPRV-----------VLLSNTQTQYSIEIQNVDVYDEGPYTCSVQ 118

  Fly   313 T-HPPRVFTTNLTVLEPPLRIIDEHERDVGDRYYKSGSTVDLQC-------------QIS----- 358
            | :.|:....:|.|...| :|: |...|:.   ...|:.:.|.|             .||     
Human   119 TDNHPKTSRVHLIVQVSP-KIV-EISSDIS---INEGNNISLTCIATGRPEPTVTWRHISPKAVG 178

  Fly   359 ----RSFFQKERQTILKSTD----SANDAVQKLINETTSELNL-------------IGNVNQTQH 402
                ..:.:.:..|..:|.|    ::||....::......:|.             :|.....|.
Human   179 FVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQC 243

  Fly   403 KFSGQDLEKYFTKFITWAKDEEPL-QGMTNRRLSVSDVWLTSRISIGDAKLSDSGNYSC 460
            :.|.....::     .|.||::.| :|  .:.:.|.:....|::...:....|.|||:|
Human   244 EASAVPSAEF-----QWYKDDKRLIEG--KKGVKVENRPFLSKLIFFNVSEHDYGNYTC 295

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr18NP_573102.1 IG_like 242..325 CDD:214653 24/94 (26%)
Ig <258..326 CDD:299845 20/79 (25%)
IGc2 <417..461 CDD:197706 12/45 (27%)
NTMNP_001338930.1 Ig 44..132 CDD:416386 26/105 (25%)
Ig strand A' 44..49 CDD:409353 2/6 (33%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 0/4 (0%)
FR2 64..70 CDD:409353 2/5 (40%)
Ig strand C 64..70 CDD:409353 2/5 (40%)
CDR2 71..83 CDD:409353 4/15 (27%)
Ig strand C' 72..76 CDD:409353 0/7 (0%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 11/44 (25%)
Ig strand D 87..94 CDD:409353 2/17 (12%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 2/8 (25%)
FR4 125..132 CDD:409353 1/6 (17%)
Ig_3 136..205 CDD:404760 12/73 (16%)
Ig strand A' 142..147 CDD:409353 1/7 (14%)
Ig strand B 153..160 CDD:409353 2/6 (33%)
Ig strand C 166..171 CDD:409353 0/4 (0%)
Ig strand D 177..180 CDD:409353 0/2 (0%)
Ig strand E 184..190 CDD:409353 0/5 (0%)
Ig strand F 197..204 CDD:409353 1/6 (17%)
Ig strand G 211..219 CDD:409353 0/7 (0%)
Ig_3 222..299 CDD:404760 15/81 (19%)
putative Ig strand A 223..229 CDD:409353 0/5 (0%)
Ig strand B 239..243 CDD:409353 0/3 (0%)
Ig strand C 252..256 CDD:409353 0/8 (0%)
Ig strand E 278..282 CDD:409353 1/3 (33%)
Ig strand F 292..297 CDD:409353 3/4 (75%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.