DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr18 and NCAM2

DIOPT Version :9

Sequence 1:NP_573102.1 Gene:dpr18 / 32572 FlyBaseID:FBgn0030723 Length:519 Species:Drosophila melanogaster
Sequence 2:XP_011527877.1 Gene:NCAM2 / 4685 HGNCID:7657 Length:874 Species:Homo sapiens


Alignment Length:283 Identity:63/283 - (22%)
Similarity:100/283 - (35%) Gaps:96/283 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   241 EAVLNCRVGMLKDKTVMWVRRTAEKVSLLTVGNVTYSGDPRIRVKFQYPNNWRLL-INPTQTEDA 304
            :|.:.|||.......|.|:....|         ||...|.|..:...  ||.::| ||.:   |.
Human   156 DAEVVCRVSSSPAPAVSWLYHNEE---------VTTISDNRFAMLAN--NNLQILNINKS---DE 206

  Fly   305 GVYMCQ----------------VSTHPPRVF----TTNLTV---------------LEPPL---- 330
            |:|.|:                :...||.:.    :.|.|.               .||.:    
Human   207 GIYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFR 271

  Fly   331 --RIIDEHERDVGDRYYKSGSTVDLQ-------------CQISRSFFQKERQTILKSTDSANDAV 380
              ::|:|:|     :|...||..:|.             |:.:....:.|:|..|:.  .....:
Human   272 NGKLIEENE-----KYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQV--FVQPHI 329

  Fly   381 QKLINETTSELNLIGNVNQTQHKFSGQDLEKYFTKFITWAKDEEPLQGMT--------NRRLSVS 437
            .:|.||||.|...:..|...:    |:.:.:     |||   :..:.|.|        :.|:.|.
Human   330 IQLKNETTYENGQVTLVCDAE----GEPIPE-----ITW---KRAVDGFTFTEGDKSLDGRIEVK 382

  Fly   438 DVWLTSRISIGDAKLSDSGNYSC 460
            ....:|.:.|.|.||||||.|.|
Human   383 GQHGSSSLHIKDVKLSDSGRYDC 405

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr18NP_573102.1 IG_like 242..325 CDD:214653 23/103 (22%)
Ig <258..326 CDD:299845 19/103 (18%)
IGc2 <417..461 CDD:197706 18/52 (35%)
NCAM2XP_011527877.1 Ig1_NCAM-2 46..137 CDD:143274
I-set 47..136 CDD:254352
I-set 142..218 CDD:254352 20/75 (27%)
IGc2 153..214 CDD:197706 20/71 (28%)
Ig 233..326 CDD:299845 17/99 (17%)
I-set 240..323 CDD:254352 15/87 (17%)
Ig5_NCAM-2 325..422 CDD:143278 26/93 (28%)
IG_like 333..420 CDD:214653 25/85 (29%)
IG_like 438..515 CDD:214653
IGc2 439..507 CDD:197706
FN3 521..613 CDD:238020
fn3 619..703 CDD:278470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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