DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr18 and dpr15

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	111/516 - (21%)
Similarity:	170/516 - (32%)	Gaps:	143/516 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 RLLTIALVI---GSQVQVLYTTSVETKSPSASEQSRNGENRSLLFDDYNKTKSTLSTADYLSATR 95
            ||:.:||:|   ..:.|...|:.:.:...:.....|....|..|..   .|.....|.|..||.|
  Fly     9 RLILLALLICLPAIRGQAEETSILNSNGTNGRAFQRTQSRREALIP---ATTQMAQTLDKASAFR 70

  Fly    96 ATLYA--------------------------------------FSSQDQDEDHSQMPIEASNAPH 122
            .|:.|                                      .|:::..|.||.. |...||..
  Fly    71 PTMAAALDAAAPNRSSNNVAINNISNNGDQRLRLTAALEANLIMSNRNVQEQHSYR-ITQDNATS 134

  Fly   123 --SPIPTKMSRGKIPMETPGSMEFSSNSLPIKNVGTTDQLTT-----VTMPTTAFASLKVDRSTM 180
              |..|...:.|..|            |:||   |.....||     .|.|||      ..|.|.
  Fly   135 AASIAPNGTAFGDAP------------SIPI---GVAPATTTTIDPATTTPTT------TTRRTT 178

  Fly   181 KQPIDSTRTRNHWTASGFARVTERPRSKHHHEHHWGPFFEEPINSATSGDNLVSAVHLFTEAVLN 245
            ::|:.:|..:...|...:..:..:                       :|          |.|.|.
  Fly   179 RRPVATTTLKPPPTIDDYQTIISQ-----------------------AG----------THAYLP 210

  Fly   246 CRVGMLKDKTVMWVRRTAEKVSLLTVGNVTYSGDPRIRVKFQ-YPNNWRLLINPTQTEDAGVYMC 309
            |.|..|..|.:.|:|  .....:|||...|:..|.|.:..|. .|..|.|.|...|.:|.|.|.|
  Fly   211 CNVKQLVKKPISWLR--MRDGHILTVDQTTFIADQRFQSVFSPNPERWSLQIKYVQLKDEGTYEC 273

  Fly   310 QVSTHPPRVFTTNLTVLEPPLRIIDEHERDVGDRYYKSGSTVDLQCQISR--------SFFQKER 366
            ||||.|......:|.::||...:|.|..|.|     |:||.|.|:|.||:        ::|..::
  Fly   274 QVSTEPKASAIVHLRIVEPKTELIGESTRHV-----KAGSQVKLRCIISQALEPPLFINWFYNQK 333

  Fly   367 QTILKSTDSANDAVQKL--------INETTSELNLIGNVNQTQHKFSGQDLEKYFTKFITWAKDE 423
            |..|.:.......::::        .:.||:......:...|....:........|.....|...
  Fly   334 QIYLHNRRGWRTEIERIDLPAEVPTTSTTTTTTTTTASTTTTTTSTTPATPSTTATGSTEGATSS 398

  Fly   424 EPLQGMTNRRLSVSDVWLTSRISIGDAKLSDSGNYSCSLGRLFTVIVQVQVLTGELPAAVQ 484
            |.|.|:    ::::..::...||..|..         .||....|.|..:..|.:|...|:
  Fly   399 ETLNGL----VTITRSYILDAISQNDVS---------ELGAAAGVAVATETSTAQLLTEVE 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	30/83 (36%)
		Ig	<258..326	CDD:299845	24/68 (35%)
		IGc2	<417..461	CDD:197706	7/43 (16%)
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	32/126 (25%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	32/97 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	42	1.000	Domainoid score	I12424
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23279
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910