DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr18 and Sdk2

DIOPT Version :9

Sequence 1:NP_573102.1 Gene:dpr18 / 32572 FlyBaseID:FBgn0030723 Length:519 Species:Drosophila melanogaster
Sequence 2:XP_006247755.1 Gene:Sdk2 / 360652 RGDID:1310397 Length:2175 Species:Rattus norvegicus


Alignment Length:561 Identity:110/561 - (19%)
Similarity:180/561 - (32%) Gaps:181/561 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 SQVQVLYTTSVE---------------TKSPSASEQSRNGENRSLLFDDYNKTKSTLSTADYLSA 93
            ::|||.|..|.|               .|:|..|...|   .:...|.|..|...:...|..|..
  Rat   108 TEVQVAYMGSFEEGEKHQSVSHGEAAVIKAPRISSFPR---PQVTWFRDGRKIPPSSRIAITLEN 169

  Fly    94 T------------RATLYAFSSQDQDEDHSQ---MPIEASNAPHSPI-PTKMSRGKIPMETPG-- 140
            |            |..:.|.:.::.|...||   :.:|....|..|| ||.:...|......|  
  Rat   170 TLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLAVENVGGPADPIAPTIIIPPKNTSVVAGTS 234

  Fly   141 --SMEFSSNSLPI---------------KNVGTTDQLTTVTMPTTAFASL----KVDRSTMKQPI 184
              :||..:|:.|:               ..:...::..|:|.|..:.|..    .:.||:...|:
  Rat   235 EVTMECVANARPLIKLHIVWKKDGALLSNGISDYNRRLTITNPMVSDAGYYECEAMLRSSSVAPV 299

  Fly   185 DSTRTRNHWTASGFARVTERPRSKHHHEHHWGPFFEEPINSATSGDNLVSAVHLFTEAVLNCRVG 249
                     |...:..|.|.|:.....|.|.....|:.::                   :.||..
  Rat   300 ---------TRGAYLSVLEPPQFVREPERHITAEMEKVVD-------------------IPCRAK 336

  Fly   250 MLKDKTVMWVRRTAEKVSLLTVGNVTYSGDPRIRVKFQYPNNWRLLINPTQTEDAGVYMC----- 309
            .:...::.|.:..|    |:.||.:|         :|:..::..|.|:....:|.|:..|     
  Rat   337 GVPPPSITWYKDAA----LVEVGKLT---------RFKQRSDGGLQISGLLPDDTGMVQCFAHNA 388

  Fly   310 ----QVSTHPPRVFTTNL--TVLEPPL--RIIDEHE----------------RDVGDRYYKSGST 350
                |.||:   :..|::  .:...||  .:||...                ...|:|...|||.
  Rat   389 AGEAQTSTY---LAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSV 450

  Fly   351 VDLQCQISRSFFQKERQTILKSTDSANDA--------VQKLINETTSEL-----NLIGNVNQTQH 402
                 |:.| |...|..::|.|....:||        ..:.::|.:::|     ..|....|.|.
  Rat   451 -----QLPR-FTLLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQS 509

  Fly   403 KFSGQDL--------EKYFTKFITWAKDEEPLQGMTNRR--------LSVSDVWLTSRISIGDAK 451
            ...|...        :...|....|.||...|...||.|        |.:|..|           
  Rat   510 VIKGTQASMVCGVTHDPRVTVRYVWEKDGATLAVETNPRIRLDRNGSLHISQTW----------- 563

  Fly   452 LSDSGNYSC---SLGRLFTVIVQVQVLTGELPAAVQHNIGS 489
            ..|.|.|:|   |.|...:....::|  .:||.|.:|.:.:
  Rat   564 SGDIGTYTCRVLSAGGNDSRNAHLRV--RQLPHAPEHPVAT 602

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr18NP_573102.1 IG_like 242..325 CDD:214653 18/93 (19%)
Ig <258..326 CDD:299845 16/78 (21%)
IGc2 <417..461 CDD:197706 14/54 (26%)
Sdk2XP_006247755.1 IG_like 43..112 CDD:214653 1/3 (33%)
IGc2 43..101 CDD:197706
IG_like 123..206 CDD:214653 15/85 (18%)
Ig 135..191 CDD:299845 12/58 (21%)
IG_like 225..307 CDD:214653 14/90 (16%)
IGc2 236..289 CDD:197706 8/52 (15%)
I-set 311..400 CDD:254352 21/123 (17%)
Ig 329..397 CDD:143165 16/99 (16%)
I-set 405..495 CDD:254352 19/95 (20%)
Ig 419..495 CDD:299845 15/81 (19%)
Ig 505..589 CDD:299845 20/94 (21%)
IG_like 505..589 CDD:214653 20/94 (21%)
FN3 593..684 CDD:238020 3/10 (30%)
FN3 696..789 CDD:238020
FN3 797..893 CDD:238020
FN3 898..986 CDD:238020
FN3 996..1090 CDD:238020
FN3 1102..1197 CDD:238020
FN3 1204..1293 CDD:238020
FN3 1304..1397 CDD:238020
FN3 1403..1487 CDD:238020
FN3 1506..1619 CDD:238020
FN3 1629..1722 CDD:238020
FN3 1727..1808 CDD:238020
FN3 1840..1919 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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