DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr18 and bdl

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster

Alignment Length:	409	Identity:	79/409 - (19%)
Similarity:	139/409 - (33%)	Gaps:	140/409 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 FARVTERPRSKHHHEHHWGPFFEEPINS-ATSGDNLVSAV------------------HLFTEAV 243
            ||:|         .|:|.|.:...|.|. .|.|.:.|.:|                  .|...|.
  Fly   305 FAKV---------DENHAGSYTCTPYNDLGTDGPSPVISVIVLRPPIFSVTPKAIYIQKLGEAAE 360

  Fly   244 LNC----RVGMLKDKTVMWVRR-----TAEKVSLLTVGNVTYSGDPRIRVKFQYPNNWRLLINPT 299
            |.|    |.|..: .:::|.|:     .|::.| |:.||:|.:|                |:.
  Fly   361 LPCEAIDRDGNNR-PSIIWGRKDGQPLPADRFS-LSGGNLTITG----------------LVE-- 405

  Fly   300 QTEDAGVYMC------------------QVSTHPPRVFTTNLT---------------------- 324
              .|.|:|.|                  .::...|...|.|.|
  Fly   406 --GDRGIYECSATNEAATITAEAELMIENIAPRAPYNLTANSTETCITIRWQPGYLRPNLEYTVW 468

  Fly   325 --VLEPP----LRIIDEHERDVGDRYYKSGSTVDL----QCQISRSFFQKE--RQTI---LKSTD 374
              ::|.|    ||::|:...:...::.:.|...:.    |.:.....|.|:  .||:   :::.|
  Fly   469 YRLMEAPEWRTLRVLDKKVMEATVQHLQPGKEYEFMVLSQDKYGDGMFSKQFRFQTLPSPIRADD 533

  Fly   375 SANDAVQKLINETTSELNLIG---NVNQTQHKFSGQDLEKYFTKFITWAKDEEPLQGMTNRRLSV 436
            .....:|..:.:.|:....:|   |:....::...         .:.|   |.|:||:...||..
  Fly   534 FDAQQLQHDLGQVTAPAGGLGAPWNLTAISNQQGW---------LLHW---EHPVQGLEGLRLYA 586

  Fly   437 SDVWL-TSRISIGDAKLSDSGNYSCSLGRLFTVIVQVQVL---TGELPAAVQH----NIGSRTEI 493
            ...|. .....||.|:..|  ||..........:.:||||   |....:...|    ::.|:.::
  Fly   587 VRWWKEPEHFLIGHAETFD--NYYQLRHLKEDTLFKVQVLAVGTETQQSVPSHELLIDVPSQRKV 649

  Fly   494 YSLAMLGHLLVLIFLFTCL 512
            .:| ::|..:.:|||...|
  Fly   650 RAL-IIGSSVGVIFLLCAL 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	23/133 (17%)
		Ig	<258..326	CDD:299845	18/114 (16%)
		IGc2	<417..461	CDD:197706	14/44 (32%)
bdl	NP_608822.1	IG_like	42..128	CDD:214653
		Ig	43..131	CDD:299845
		I-set	153..242	CDD:254352
		Ig	157..242	CDD:299845
		Ig_2	252..337	CDD:290606	12/40 (30%)
		IG_like	260..327	CDD:214653	8/30 (27%)
		I-set	341..428	CDD:254352	20/108 (19%)
		IGc2	356..419	CDD:197706	19/84 (23%)
		FN3	435..524	CDD:238020	13/88 (15%)
		FN3	554..636	CDD:238020	21/95 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810