DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr18 and Kirrel1

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	XP_006232737.1	Gene:	Kirrel1 / 310695	RGDID:	727883	Length:	805	Species:	Rattus norvegicus

Alignment Length:	301	Identity:	59/301 - (19%)
Similarity:	102/301 - (33%)	Gaps:	97/301 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   244 LNCRVGMLKD-KTVMWVRRTAEKVSLLTVGNVTYSGDPRIRVKFQYPNNWRLLINPTQTEDAGVY 307
            |.||....|. .|::|.|...::...:|...:...|.....:.       :|||.||..:...|:
  Rat   173 LTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTIS-------QLLIQPTDLDIGRVF 230

  Fly   308 MC---------------QVSTHPPRVFTTNL---TVLEPPLRII-----DEHERDVGDRYYKSGS 349
            .|               ::..|.|...|.::   ||||.. |:|     ..:...:|.|:.|.|.
  Rat   231 TCRSMNEAIPNGKETSIELDVHHPPTVTLSIEPQTVLEGE-RVIFTCQATANPEILGYRWAKGGF 294

  Fly   350 TVD------LQCQISRSFFQKERQ-TILKSTDSANDAVQKLIN------------ETTSELN--- 392
            .::      .:..:..|||.:... .:.....|.|  |..|:|            .||:::.
  Rat   295 LIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTN--VSTLVNVHFAPRIVVYPKPTTTDIGSDV 357

  Fly   393 -----LIGNVNQTQHKFSGQDLEKYFTKFITWAKDEE----------PLQGMTNRRLSVSDVWLT 442
                 .:||...|                :||.|.:.          |...::.:.||.|:..|.
  Rat   358 TLTCVWVGNPPLT----------------LTWTKKDSNMGPRLPGSPPEANLSAQVLSNSNQLLL 406

  Fly   443 SRISIGDAKLSDSGNYSCSLGRLFTVIVQVQVLTGELPAAV 483
            ..::..||     |.|:|.     .::.::.|...|:|..|
  Rat   407 KSVTQADA-----GTYTCR-----AIVPRIGVAEREVPLYV 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	19/99 (19%)
		Ig	<258..326	CDD:299845	15/85 (18%)
		IGc2	<417..461	CDD:197706	12/53 (23%)
Kirrel1	XP_006232737.1	I-set	54..148	CDD:254352
		Ig	57..148	CDD:299845
		Ig2_KIRREL3-like	170..251	CDD:143236	16/84 (19%)
		I-set	255..336	CDD:254352	18/83 (22%)
		Ig_2	259..337	CDD:290606	18/80 (23%)
		Ig_2	340..437	CDD:290606	21/122 (17%)
		IG_like	346..437	CDD:214653	21/116 (18%)
		Ig5_KIRREL3	439..536	CDD:143306
		IG_like	451..536	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810