DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr18 and sdk

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001284756.1	Gene:	sdk / 31017	FlyBaseID:	FBgn0021764	Length:	2265	Species:	Drosophila melanogaster

Alignment Length:	345	Identity:	66/345 - (19%)
Similarity:	117/345 - (33%)	Gaps:	105/345 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 LPIKNVGTTDQLTTVTMPTTAFASLKVDRSTMKQPIDSTRTRNHWTASGFARVTERPRSKHHHEH 213
            |.|...|.....|.:.:.|.. |..:|.|  :.|| ...|.|......|..:.:|...|....|.
  Fly   434 LAINEAGENSASTWLRVKTKT-AKNRVKR--LAQP-RILRVRASHAGLGSEKGSESGSSDRRKEF 494

  Fly   214 HW--GPFFEEPINSATSGDNLVSAVHLFTEAVLNCRVGMLKDKTVMWVRRTAEKVSLLTVGNVTY 276
            .:  .|..|.|..:.|:.|.        .:|.::||.....:..:.|:....:.|.:.:...:..
  Fly   495 RFASAPIMELPPQNVTALDG--------KDATISCRAVGSPNPNITWIYNETQLVDISSRVQILE 551

  Fly   277 SGDPRIRVKFQYPNNWRLLINPTQTEDAGVYMCQVSTHPPRV-------FTTNLTVLEPPLRIID 334
            |||              |||:..::.|||:|:|..:.....|       ......:::||:
  Fly   552 SGD--------------LLISNIRSVDAGLYICVRANEAGSVKGEAYLSVLVRTQIIQPPV---- 598

  Fly   335 EHERDVGDRYYKSGSTVDLQCQISRSFFQKERQTILKSTDSANDAVQKLINETTSELNLIGNVNQ 399
                   |.....|.|..|||::|                              |:.::..|::
  Fly   599 -------DTTVLLGLTATLQCKVS------------------------------SDPSVPYNID- 625

  Fly   400 TQHKFSGQDLEKYFTKFITWAKDEEPLQGMTN-RRLSVSDVWLTSRISIGDAKLSDSGNYSC--- 460
                               |.::.:....::| :|:.|.   ...::.|...:.||.|:|:|
  Fly   626 -------------------WYREGQSSTPISNSQRIGVQ---ADGQLEIQAVRASDVGSYACVVT 668

  Fly   461 SLGRLFTVIVQVQVLTGELP 480
            |.|...|...::.|:  |||
  Fly   669 SPGGNETRAARLSVI--ELP 686

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	17/89 (19%)
		Ig	<258..326	CDD:299845	14/74 (19%)
		IGc2	<417..461	CDD:197706	10/47 (21%)
sdk	NP_001284756.1	Ig	71..157	CDD:299845
		I-set	72..150	CDD:254352
		Ig	172..245	CDD:299845
		IG_like	280..356	CDD:214653
		Ig	280..343	CDD:299845
		IG_like	375..450	CDD:214653	4/15 (27%)
		Ig	378..447	CDD:143165	3/12 (25%)
		Ig	506..587	CDD:299845	19/102 (19%)
		IG_like	506..587	CDD:214653	19/102 (19%)
		I-set	592..682	CDD:254352	24/153 (16%)
		Ig	595..682	CDD:299845	24/150 (16%)
		FN3	686..789	CDD:238020	1/1 (100%)
		FN3	798..893	CDD:238020
		FN3	901..1005	CDD:238020
		fn3	1011..1094	CDD:278470
		FN3	1108..1202	CDD:238020
		FN3	1210..1308	CDD:238020
		fn3	1317..1402	CDD:278470
		FN3	1415..1507	CDD:238020
		FN3	1513..1608	CDD:238020
		fn3	1617..1708	CDD:278470
		FN3	1722..1823	CDD:238020
		FN3	1828..1920	CDD:238020
		FN3	1927..2016	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810