DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr18 and Iglon5

DIOPT Version :9

Sequence 1:NP_573102.1 Gene:dpr18 / 32572 FlyBaseID:FBgn0030723 Length:519 Species:Drosophila melanogaster
Sequence 2:XP_218634.5 Gene:Iglon5 / 308557 RGDID:1305344 Length:336 Species:Rattus norvegicus


Alignment Length:332 Identity:75/332 - (22%)
Similarity:122/332 - (36%) Gaps:85/332 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   219 FEEPINSAT--SGDNLVSAVHLFTEAVLNCRVGMLKDK---TVMWVRRTAEKVSLLTVGNVTYSG 278
            |..|.::.|  .|||          |.|:|.:    |:   .|.|:.|:    ::|..||..::.
  Rat    35 FSSPADNYTVCEGDN----------ATLSCFI----DEHVTRVAWLNRS----NILYAGNDRWTS 81

  Fly   279 DPRIRVKFQYPNNWRLLINPTQTEDAGVYMCQVST-HPPRVFTTNL-TVLEPPLRIIDEHERDVG 341
            |||:|:....|..:.:||......|.|:|.|...| |.|  :||.: .::..|.||::...... 
  Rat    82 DPRVRLLINTPEEFSILITQVGLGDEGLYTCSFQTRHQP--YTTQVYLIVHVPARIVNISSPVA- 143

  Fly   342 DRYYKSGSTVDLQC-------------QISRSFFQKERQTILKSTD------------------S 375
               ...|..|:|.|             |: |..|..|.: ||:.:|                  |
  Rat   144 ---VNEGGNVNLLCLAVGRPEPTVTWRQL-RDGFTSEGE-ILEISDIQRGQAGEYECVTHNGVNS 203

  Fly   376 ANDAVQKL--------INETTSELNLIGNVNQTQHKFSG---QDLEKYFTKFITWAKDEEPLQGM 429
            |.|:.:.|        |.:.||....:|.....:.:...   .|.:        |.||:..|...
  Rat   204 APDSRRVLVTVNYPPTITDVTSARTALGRAALLRCEAMAVPPADFQ--------WYKDDRLLSSG 260

  Fly   430 TNRRLSVSDVWLTSRISIGDAKLSDSGNYSC-SLGRLFTVIVQVQVL-TGELPAAVQHNIGSRTE 492
            :...|.|......|.:...:......|||:| :..||......:::| .|.|..:.....|..|.
  Rat   261 SAEGLKVQTERTRSMLLFANVSARHYGNYTCRAANRLGASSASMRLLRPGSLENSAPRPPGPLTL 325

  Fly   493 IYSLAML 499
            :.:|:.|
  Rat   326 LSALSWL 332

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr18NP_573102.1 IG_like 242..325 CDD:214653 26/87 (30%)
Ig <258..326 CDD:299845 21/69 (30%)
IGc2 <417..461 CDD:197706 11/44 (25%)
Iglon5XP_218634.5 Ig 41..129 CDD:416386 30/107 (28%)
Ig strand A' 41..46 CDD:409353 1/4 (25%)
Ig strand B 48..56 CDD:409353 5/17 (29%)
CDR1 56..60 CDD:409353 1/7 (14%)
FR2 61..68 CDD:409353 2/6 (33%)
Ig strand C 61..67 CDD:409353 2/5 (40%)
CDR2 69..79 CDD:409353 3/13 (23%)
Ig strand C' 71..74 CDD:409353 1/2 (50%)
Ig strand C' 76..79 CDD:409353 1/2 (50%)
FR3 80..115 CDD:409353 11/34 (32%)
Ig strand D 84..91 CDD:409353 2/6 (33%)
Ig strand E 94..100 CDD:409353 1/5 (20%)
Ig strand F 107..115 CDD:409353 3/7 (43%)
CDR3 116..120 CDD:409353 2/3 (67%)
Ig strand G 120..129 CDD:409353 3/10 (30%)
FR4 122..129 CDD:409353 2/6 (33%)
Ig strand A 132..137 CDD:409353 3/4 (75%)
Ig_3 134..199 CDD:404760 13/70 (19%)
Ig strand A' 140..145 CDD:409353 0/8 (0%)
Ig strand B 148..157 CDD:409353 3/8 (38%)
Ig strand C 163..167 CDD:409353 0/3 (0%)
Ig strand D 174..177 CDD:409353 0/2 (0%)
Ig strand E 178..183 CDD:409353 2/5 (40%)
Ig strand F 191..199 CDD:409353 0/7 (0%)
Ig_3 217..295 CDD:404760 16/85 (19%)
putative Ig strand A 218..224 CDD:409353 1/5 (20%)
Ig strand B 234..238 CDD:409353 0/3 (0%)
Ig strand C 247..251 CDD:409353 1/11 (9%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 3/4 (75%)
Ig strand G 301..304 CDD:409353 0/2 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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