DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr18 and Ncam2

DIOPT Version :9

Sequence 1:NP_573102.1 Gene:dpr18 / 32572 FlyBaseID:FBgn0030723 Length:519 Species:Drosophila melanogaster
Sequence 2:NP_981954.2 Gene:Ncam2 / 288280 RGDID:1303131 Length:837 Species:Rattus norvegicus


Alignment Length:284 Identity:64/284 - (22%)
Similarity:105/284 - (36%) Gaps:98/284 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   241 EAVLNCRVGMLKDKTVMWVRRTAEKVSLLTVGNVTYSGDPRIRVKFQYPNNWRLL-INPTQTEDA 304
            :|.:.|||.......|.|:....|         ||...|.|..|...  ||.::| ||.:   |.
  Rat   131 DAEVVCRVSSSPAPAVSWLYHNEE---------VTTIPDNRFAVLAN--NNLQILNINKS---DE 181

  Fly   305 GVYMCQ----------------VSTHPPRVF----TTNLTV---------------LEPPL---- 330
            |:|.|:                :...||.:.    :.|.|.               .:|.:    
  Rat   182 GIYRCEGRVEARGEIDFRDIIVIVNVPPAIVMPQKSFNATAERGEEMTLTCKASGSPDPAISWFR 246

  Fly   331 --RIIDEHERDVGDRYYKSGSTVDLQCQISRSFFQKERQT-ILKSTDSAND-------------A 379
              ::|:|:|     :|...||..:|..   |:...|:..: :.|:|:.|.:             .
  Rat   247 NGKLIEENE-----KYILKGSNTELTV---RNIINKDGGSYVCKATNKAGEDQKQAFLQVFVQPH 303

  Fly   380 VQKLINETTSELNLIGNVNQTQHKFSGQDLEKYFTKFITWAKDEEPLQGMT--------NRRLSV 436
            :.:|.||||||...:..:.:.:    |:.:.:     |||   :..:.|:|        :.|:.|
  Rat   304 ILQLKNETTSENGHVTLICEAE----GEPVPE-----ITW---KRAIDGVTFSEGDKSPDGRIEV 356

  Fly   437 SDVWLTSRISIGDAKLSDSGNYSC 460
            ......|.:.|.|.||||||.|.|
  Rat   357 KGQHGRSSLHIRDVKLSDSGRYDC 380

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr18NP_573102.1 IG_like 242..325 CDD:214653 24/103 (23%)
Ig <258..326 CDD:299845 20/103 (19%)
IGc2 <417..461 CDD:197706 18/52 (35%)
Ncam2NP_981954.2 IgI_1_NCAM-2 21..113 CDD:409452
Ig strand B 38..42 CDD:409452
Ig strand C 50..54 CDD:409452
Ig strand E 76..80 CDD:409452
Ig strand F 90..95 CDD:409452
Ig strand G 104..107 CDD:409452
IGc2 128..189 CDD:197706 21/71 (30%)
Ig strand B 130..139 CDD:409353 3/7 (43%)
Ig strand C 145..153 CDD:409353 2/7 (29%)
Ig strand C' 156..159 CDD:409353 1/2 (50%)
Ig strand D 162..167 CDD:409353 2/4 (50%)
Ig strand E 168..175 CDD:409353 2/8 (25%)
IgI_1_MuSK 209..298 CDD:409562 16/96 (17%)
Ig strand B 228..232 CDD:409562 0/3 (0%)
Ig strand C 241..245 CDD:409562 0/3 (0%)
Ig strand E 264..268 CDD:409562 1/3 (33%)
Ig strand F 278..283 CDD:409562 0/4 (0%)
Ig strand G 291..294 CDD:409562 0/2 (0%)
Ig 300..397 CDD:416386 26/93 (28%)
Ig strand A 300..305 CDD:409353 0/4 (0%)
Ig strand A' 309..313 CDD:409353 3/3 (100%)
Ig strand B 317..325 CDD:409353 0/7 (0%)
Ig strand C 331..337 CDD:409353 3/13 (23%)
Ig strand C' 340..343 CDD:409353 1/2 (50%)
Ig strand D 353..359 CDD:409353 2/5 (40%)
Ig strand E 362..368 CDD:409353 1/5 (20%)
Ig strand F 376..384 CDD:409353 3/5 (60%)
Ig strand G 387..397 CDD:409353
Ig_3 401..479 CDD:404760
Ig strand B 418..422 CDD:409353
Ig strand C 431..435 CDD:409353
Ig strand E 458..462 CDD:409353
Ig strand F 472..477 CDD:409353
Ig strand G 486..489 CDD:409353
FN3 496..588 CDD:238020
fn3 594..678 CDD:394996
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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