Protein Alignment dpr18 and NEGR1

DIOPT Version :9

• Sequence 1: NP_573102.1
• Gene: dpr18 / 32572
• FlyBaseID: FBgn0030723
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 73/325 - (22%)
• Similarity: 121/325 - (37%)
• Gaps: 67/325 - (20%)

  Fly   230 DNLVSAVHLFTEAVLNCRVGMLKD--KTVMWVRRTAEKVSLLTVGNVTYSGDPRIRVKFQYPNNW 292
            ||::  |.....|||.|   .|:|  ....|:.|:    |::..|...:|.|||:.:......::
Human    46 DNMM--VRKGDTAVLRC---YLEDGASKGAWLNRS----SIIFAGGDKWSVDPRVSISTLNKRDY 101

  Fly   293 RLLINPTQTEDAGVYMCQVST-HPPRVFTTNLTVLEPPLRIIDEHERDVGDRYYKSGSTVDLQC- 355
            .|.|......|.|.|.|.|.| |.||....:|||..|| :|.|..    .|.....|:.|.|.|
Human   102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPP-KIYDIS----NDMTVNEGTNVTLTCL 161

  Fly   356 ------------QISRSFFQKERQTILK----STDSANDAVQKLINETT----SELNLIGNVNQT 400
                        .||.|....|....|.    :.|.|.:......|:.:    .::.::.|...|
Human   162 ATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPT 226

  Fly   401 QHKFSGQDLEKYFTKFI------------TWAKDEEPL----QGMTNRRLSVSDVWLTSRISIGD 449
            ..:.....:....:..|            .|.|.|:.|    ||:..:..|...:     :::.:
Human   227 IQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSI-----LTVTN 286

  Fly   450 AKLSDSGNYSC-SLGRLFTVIVQVQVLTGELPAAVQHNI-GSRTEIYSLAMLGHLLVLIFLFTCL 512
            ......|||:| :..:|.|....:.:   ..|:..|:.| ||...::|   ..:|::.:..||.:
Human   287 VTQEHFGNYTCVAANKLGTTNASLPL---NPPSTAQYGITGSADVLFS---CWYLVLTLSSFTSI 345

  Fly   513  512
            Human   346  345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	26/85 (31%)
		Ig	<258..326	CDD:299845	21/68 (31%)
		IGc2	<417..461	CDD:197706	12/60 (20%)
NEGR1	NP_776169.2	IG	47..135	CDD:214652	28/96 (29%)
		IGc2	152..210	CDD:197706	12/57 (21%)
		Ig_3	225..301	CDD:372822	13/80 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810