DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr18 and Lrit1

DIOPT Version :9

Sequence 1:NP_573102.1 Gene:dpr18 / 32572 FlyBaseID:FBgn0030723 Length:519 Species:Drosophila melanogaster
Sequence 2:NP_647547.2 Gene:Lrit1 / 246214 RGDID:628607 Length:623 Species:Rattus norvegicus


Alignment Length:620 Identity:119/620 - (19%)
Similarity:187/620 - (30%) Gaps:230/620 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 RLPKGYRTLSPASNAAQTLPLSYNSQTSLSLLRLLTI-------------------ALVIGSQVQ 47
            |:|.  .|..|.|...| |.|.||:.:.||.|.|..:                   ||....|:|
  Rat    73 RVPG--ETFRPLSRLEQ-LWLPYNALSELSTLMLRGLRRLRELRLPGNHLVTFPWAALKDTPQLQ 134

  Fly    48 V--LYTTSVETKSPSASEQSRN------GENRSL-LFDDYNKTKSTLSTADYLSATRATLYAFSS 103
            :  |....:.|..|.|.....|      ..|:.: |.::...|.:.|.|..|||:.|..| ....
  Rat   135 LLDLQANRLSTLPPEAVHFLENLTFLDLSNNQLMRLPEELLDTWAHLKTGPYLSSRRTRL-VLGL 198

  Fly   104 QDQ---------DEDH-------SQMPIEA---SNAPHSPIPTKMSRGKI-----PMETPGSMEF 144
            ||.         |..|       :.:.|||   ..:|.|......|:.::     |...||    
  Rat   199 QDNPWVCDCRLYDLVHLLDGWASNLIFIEARLRCGSPRSLAGVAFSQLELRKCQSPELRPG---- 259

  Fly   145 SSNSLPIKNVGTTDQLTTVTMPTTAFASLKVDRSTMKQPIDSTRTRNHWTASGFARVTERPRSKH 209
                           :|::..|..:...|:...:.:..|..|.|           |...||.:..
  Rat   260 ---------------VTSIISPLGSTVLLRCGATGIPGPEMSWR-----------RANGRPLNGT 298

  Fly   210 HHEH------HWGPFFEEPINSA-TSGDNLVSAVHLF--TEAVLNCRVGMLKDKT-------VMW 258
            .|:.      .| ...:.|:.|. .|||.:..|.:..  :|.:::..|...:..|       .:|
  Rat   299 VHQEVSSDGSSW-TLLDLPVVSLFDSGDYICQAKNFLGASETLISLIVTEPQTSTEYTGIPGALW 362

  Fly   259 VR--------------------RTAEKVSLLTVGNVTYSGDPRIRVKFQYPNNWRLLINPTQTED 303
            .|                    ...|.|:|.|..:|     |.|:.:....|        .|.:.
  Rat   363 ARTGEGAEAAAYNNKLVARHVPHVPEPVALATKPSV-----PSIKEELPLQN--------FQMDV 414

  Fly   304 AGVYMCQVSTHPPRVFTTNLTVLEPPLRIIDEHERDVGDRYY----------------------- 345
            .|.:..:.|.|.......:|.|              |||.|:                       
  Rat   415 PGEFSREPSEHQETQMVRSLKV--------------VGDTYHSVSLVWKAPQAGNTTAFSVLYAV 465

  Fly   346 --------------KSGSTVD--------LQCQISRSFFQKERQTILKSTDSANDA--VQKLINE 386
                          |:..|::        :.|...|.....:.|.::.|||...||  .|:|||.
  Rat   466 FGQRDMRRMTVEAGKTSVTIEGLAPKTKYVACVCVRGLVPTKEQCVIFSTDEVVDAEGTQRLINM 530

  Fly   387 TTSELNLI-----------GNVNQTQHK--------FSGQ--DLEKYFTKFITWAKDEEPLQGMT 430
            ....:..|           |.:.:..||        .||.  :||:.       ...|:..:.::
  Rat   531 VVISVAAIIALPPTLLVCCGALRRRCHKCRAGGSAEASGAYVNLERL-------GHSEDGSEELS 588

  Fly   431 NRRLSVSDVWLTSRISIGDAKLSDSG-----NYSC 460
            ...||.:|..|::|.|:....|...|     .|.|
  Rat   589 RSSLSEADRLLSARSSLDSQVLGVRGGRRINEYFC 623

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr18NP_573102.1 IG_like 242..325 CDD:214653 17/109 (16%)
Ig <258..326 CDD:299845 15/87 (17%)
IGc2 <417..461 CDD:197706 11/49 (22%)
Lrit1NP_647547.2 LRRNT 23..61 CDD:214470
LRR 1 60..81 3/9 (33%)
LRR_8 63..143 CDD:290566 19/72 (26%)
leucine-rich repeat 64..84 CDD:275378 4/12 (33%)
LRR 2 84..105 9/21 (43%)
leucine-rich repeat 85..132 CDD:275378 11/47 (23%)
LRR 3 108..128 1/19 (5%)
LRR_8 131..>176 CDD:290566 9/44 (20%)
LRR_4 131..172 CDD:289563 9/40 (23%)
LRR 4 132..153 6/20 (30%)
leucine-rich repeat 133..156 CDD:275378 5/22 (23%)
LRR 5 156..177 3/20 (15%)
leucine-rich repeat 157..180 CDD:275378 3/22 (14%)
leucine-rich repeat 181..205 CDD:275378 9/24 (38%)
TPKR_C2 201..>240 CDD:301599 7/38 (18%)
Ig 257..345 CDD:299845 20/118 (17%)
IG_like 267..345 CDD:214653 16/89 (18%)
FN3 431..501 CDD:214495 9/83 (11%)
LRR 6 525..548 5/22 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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