DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr18 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	XP_011240777.1	Gene:	Igsf9b / 235086	MGIID:	2685354	Length:	1443	Species:	Mus musculus

Alignment Length:	419	Identity:	79/419 - (18%)
Similarity:	127/419 - (30%)	Gaps:	139/419 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 TVTMPTTAFASLKVDRSTMKQPIDSTRTRNHWTASGFARVTERPRSKH---------------HH 211
            ::||..|||.:.|...:.:|:......:..:..:.|...||...|...               |.
Mouse   158 SITMTCTAFGNPKPIVTWLKEGTLLGASAKYQVSDGSLTVTSVSREDRGAYTCRAYSIQGEAVHT 222

  Fly   212 EH---HWGPFFEEPINSATSGDNLVSAVHLFTEAVLNCRV----GMLKDKTVMWVRRTAEKVSLL 269
            .|   ...||...|..:.|        |::..:|:|.||.    |.|   |..|..:..
Mouse   223 THLLVQGPPFIVSPPENIT--------VNISQDALLTCRAEAYPGNL---TYTWYWQDE------ 270

  Fly   270 TVGNVTYSGDPRIRVKFQYPNNWRLLINPT------QTEDAGVYMCQVST--------------- 313
               ||.:..|.::||        |:||:.|      :.||||.|.|..|.
Mouse   271 ---NVYFQNDLKLRV--------RILIDGTLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYLTVQ 324

  Fly   314 HPPRVFTTNLTV---------------LEPPLRIIDEHERDVGDRYYKSGSTVDLQCQISRSFFQ 363
            :|.||......:               .|||..::         ::.|.|..:.::..:..:..:
Mouse   325 YPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVV---------KWNKDGRPLQVEKNLGWTLME 380

  Fly   364 KERQTILKSTDSANDAVQKLINETTSELNLIGNVNQTQHKFSGQDLEKYFT-------------- 414
            .....|.::|:.|      |...|....|.:|.:.|:...........|||
Mouse   381 DGSIRIEEATEEA------LGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRE 439

  Fly   415 ------------KFITWAKDEEPLQGMTNRRLSVSDVWLTSRISIGDAKLSDSGNYSCSLGRLFT 467
                        ..|||.|..:|.:...|...|.|       :........|.|.:.|....:.|
Mouse   440 LLIPCAAAGDPFPVITWRKVGKPSRSKHNALPSGS-------LQFRALSKEDHGEWECVATNVVT 497

  Fly   468 VIVQVQVLT-----GELPAAVQHNIGSRT 491
            .|.....||     ...|.:|:.::...|
Mouse   498 SITASTHLTVIGTSPHAPGSVRVHVSMTT 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	27/107 (25%)
		Ig	<258..326	CDD:299845	20/103 (19%)
		IGc2	<417..461	CDD:197706	10/43 (23%)
Igsf9b	XP_011240777.1	Ig	43..117	CDD:319273
		I-set	141..227	CDD:369462	13/68 (19%)
		Ig	231..323	CDD:386229	29/119 (24%)
		Ig	<355..416	CDD:386229	11/75 (15%)
		Ig	440..504	CDD:319273	13/70 (19%)
		FN3	512..607	CDD:238020	3/15 (20%)
		FN3	623..705	CDD:238020
		PHA03247	<900..1248	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900