DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr18 and IGSF9B

DIOPT Version :9

Sequence 1:NP_573102.1 Gene:dpr18 / 32572 FlyBaseID:FBgn0030723 Length:519 Species:Drosophila melanogaster
Sequence 2:NP_001264214.1 Gene:IGSF9B / 22997 HGNCID:32326 Length:1437 Species:Homo sapiens


Alignment Length:400 Identity:77/400 - (19%)
Similarity:125/400 - (31%) Gaps:122/400 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   162 TVTMPTTAFASLKVDRSTMKQPIDSTRTRNHWTASGFARVTERPRSKH---------------HH 211
            ::||..|||.:.|...:.:|:......:..:..:.|...||...|...               |.
Human   156 SITMTCTAFGNPKPIVTWLKEGTLLGASGKYQVSDGSLTVTSVSREDRGAYTCRAYSIQGEAVHT 220

  Fly   212 EH---HWGPFFEEPINSATSGDNLVSAVHLFTEAVLNCRV----GMLKDKTVMWVRRTAEKVSLL 269
            .|   ...||...|..:.|        |::..:|:|.||.    |.|   |..|..:..      
Human   221 THLLVQGPPFIVSPPENIT--------VNISQDALLTCRAEAYPGNL---TYTWYWQDE------ 268

  Fly   270 TVGNVTYSGDPRIRVKFQYPNNWRLLINPT------QTEDAGVYMCQVST--------------- 313
               ||.:..|.::||        |:||:.|      :.||:|.|.|..|.               
Human   269 ---NVYFQNDLKLRV--------RILIDGTLIIFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQ 322

  Fly   314 HPPRVFTTNLTV---------------LEPPLRIIDEHERDVGDRYYKSGSTVDLQCQISRSFFQ 363
            :|.||......:               .|||..::         ::.|.|..:.::..:..:..:
Human   323 YPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVV---------KWNKDGRPLQVEKNLGWTLME 378

  Fly   364 KERQTILKSTDSANDAVQKLINETTSELNLIGNVNQTQHKFSGQDLEKYFTKFITWAKDEE---- 424
            .....|.::|:.|      |...|....|.:|.:.|:...........|||....|...:|    
Human   379 DGSIRIEEATEEA------LGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRE 437

  Fly   425 ----------PLQGMTNRRLSVSDVWLTSRISIGDAKL-----SDSGNYSCSLGRLFTVIVQVQV 474
                      |...:|.|::........|.:..|..:.     .|.|.:.|....:.|.|.....
Human   438 LLIPCAAAGDPFPVITWRKVGKPSRSKHSALPSGSLQFRALSKEDHGEWECVATNVVTSITASTH 502

  Fly   475 LT--GELPAA 482
            ||  |..|.|
Human   503 LTVIGTSPHA 512

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr18NP_573102.1 IG_like 242..325 CDD:214653 26/107 (24%)
Ig <258..326 CDD:299845 19/103 (18%)
IGc2 <417..461 CDD:197706 9/62 (15%)
IGSF9BNP_001264214.1 IG_like 30..115 CDD:214653
Ig 41..115 CDD:143165
I-set 139..225 CDD:254352 13/68 (19%)
IGc2 153..210 CDD:197706 11/53 (21%)
I-set 229..321 CDD:254352 28/119 (24%)
Ig 235..321 CDD:299845 25/113 (22%)
IG_like 331..414 CDD:214653 13/97 (13%)
Ig <353..414 CDD:299845 11/75 (15%)
IG_like 426..505 CDD:214653 13/78 (17%)
Ig 442..505 CDD:299845 11/62 (18%)
FN3 510..601 CDD:238020 1/2 (50%)
FN3 617..699 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 758..817
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 911..1081
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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