DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr18 and zig-3

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_509336.1	Gene:	zig-3 / 192088	WormBaseID:	WBGene00006980	Length:	251	Species:	Caenorhabditis elegans

Alignment Length:	179	Identity:	36/179 - (20%)
Similarity:	55/179 - (30%)	Gaps:	85/179 - (47%)

- Green bases have known domain annotations that are detailed below.

  Fly   308 MCQVSTHP--------------PRVFTTNLTVLEPPLRIIDEHERDVGDRYYKSGSTVDLQCQIS 358
            :..:|.||              ..:.:|:||. :|.|:||:..|    |....:|.:|.|:|.:
Worm     9 LAAISAHPLSSGEMRAAVSNLVREIDSTHLTT-KPSLKIIEGLE----DNTVSTGESVTLRCDV- 67

  Fly   359 RSFFQKERQTILKSTDSANDAVQKLINETTSELNLIGNVNQTQHKFSGQDLEKYFTKFITWAKDE 423
                        .||.                                       |..|.|.||.
Worm    68 ------------LSTP---------------------------------------TGVIYWEKDG 81

  Fly   424 EPLQGMTNRRLSVSDVWL------------TSRISIGDAKLSDSGNYSC 460
            :.:||  ::.|:|.:..|            ||...|..|.|...|:|.|
Worm    82 QRIQG--DKELNVFEKVLNAMGPTVESGIITSSYQIPCANLHHIGSYKC 128

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	5/30 (17%)
		Ig	<258..326	CDD:299845	6/31 (19%)
		IGc2	<417..461	CDD:197706	17/56 (30%)
zig-3	NP_509336.1	I-set	45..145	CDD:254352	28/142 (20%)
		Ig	61..142	CDD:143165	23/122 (19%)
		IG_like	177..244	CDD:214653
		Ig	<191..237	CDD:299845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900