DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment dpr18 and zig-2

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_510069.1	Gene:	zig-2 / 192087	WormBaseID:	WBGene00006979	Length:	238	Species:	Caenorhabditis elegans

Alignment Length:	275	Identity:	50/275 - (18%)
Similarity:	85/275 - (30%)	Gaps:	78/275 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 DYNKTKSTLSTADYLSATRATLYAFSSQDQDEDHSQMPIEASNAPHSPIPTKMSRGKIPMETPGS 141
            |:.|....|.:...|..||      :..|.:....:..:.:..|..:|:|              |
Worm    19 DHQKPIRALDSQPLLKFTR------TPNDSNVTFGEKFVLSCGANGAPLP--------------S 63

  Fly   142 MEFSSNSLPIKNVGTTDQLTTVTMPTTAFASLKVDRSTMKQPIDSTRTRNHWTASGFARVTERPR 206
            :.:..|.:.|:...|::....:.......::..:..|..:.|..:.|     .:..:..:.:...
Worm    64 IYWELNGMRIQGEETSNVYENILNDGKQVSNAAMVSSHYRIPCATAR-----NSGAYKCIIDNGL 123

  Fly   207 SKHHH---------------EHHWGPFFEEPINSATSGDNLVSAVHLFTEAVLNCRVGMLKDKTV 256
            :|..|               ..:..||....::......|  :||      .|:||    .:...
Worm   124 TKLEHVAKVFVGGNKTNCALNDNGAPFISMTVDFRLEISN--NAV------ALSCR----SETAT 176

  Fly   257 MWVRRTAEKVSLLTVGNVTY----SGDPRIRVKFQYPNNWRLLINPTQTEDAGVYMCQVSTHPPR 317
            .|.....|:  |||.....|    |||              |:|......|.|.|.|....|
Worm   177 EWSWHKGEQ--LLTNDGERYQMFPSGD--------------LIIRNISWSDMGEYNCTARNH--- 222

  Fly   318 VF--TTNLTVLEPPL 330
             |  ||.:|.|.|.|
Worm   223 -FGETTAITFLYPTL 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	22/88 (25%)
		Ig	<258..326	CDD:299845	20/73 (27%)
		IGc2	<417..461	CDD:197706
zig-2	NP_510069.1	I-set	34..134	CDD:254352	15/124 (12%)
		Ig	34..121	CDD:299845	13/111 (12%)
		Ig	<179..232	CDD:299845	19/72 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900