DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr18 and rig-3

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_509155.1	Gene:	rig-3 / 180958	WormBaseID:	WBGene00004370	Length:	487	Species:	Caenorhabditis elegans

Alignment Length:	429	Identity:	83/429 - (19%)
Similarity:	139/429 - (32%)	Gaps:	134/429 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 SPASNAAQTLPLS-----YNSQT-SLSLLRLLTIALVIGSQVQVLYTTSVETKSPSASEQSRNGE 69
            ||:||.|..:.:|     |::.| ::...:.|.::.|..|..|: :.:.:..|  .|:..:.:||
Worm    26 SPSSNEANPIVISSEAMDYDTNTITVREGKKLMVSCVFESDEQI-HKSDLLWK--QANGNNIDGE 87

  Fly    70 NRSLLF--------DDYNKTKSTLSTADYLSATRAT-LYAFSSQDQDEDHSQMPIEASNAP---- 121
            :...||        ..:.||....|:..    ||.| ||..:.:....::.:..|:....|
Worm    88 SNPSLFSVILNEKGSKHRKTSLHFSSVH----TRDTGLYTCTGRTAGGENFEKTIKLVVLPAIEW 148

  Fly   122 -----------HSPIP----TKMSRGKIPM--ETPGSMEFSSNSLPIKNVGTTDQLTTVTMPTTA 169
                       ..||.    .|...||.||  .|.|      |..|:     .:::.|:......
Worm   149 NDKDTVKGALLGEPITIDCGVKGPSGKEPMIQMTNG------NGEPL-----DEEIWTIAGNEAT 202

  Fly   170 FASLKVDRSTMKQPIDSTRTRNHWTASGFARVTERPRSKHHHEHHWGPFFE-EPINSATSGDNLV 233
            ..|||.:.:.:.....:.......:...|..|   .|...:.|.:..|.|| |.....|..||.|
Worm   203 IDSLKKEHAELTVSCITIEMHQETSKEEFPVV---DRKDVNIEVYTLPEFETEESVQYTVIDNHV 264

  Fly   234 SAVHLFTEAVLNCRVGMLKDKTVMWVRRTAEKVSLLTVGNVT-YSGDPRIRVKFQY--------P 289
                  .:|::.|.|                ..|...|.:.| |.||..|::..::        .
Worm   265 ------RDAIIYCNV----------------THSFPPVRHYTFYHGDEEIKMSDKFNIFVNVGVS 307

  Fly   290 NNWRLLINPTQTEDAGVYMCQV------STHPPRVFTTNLTVLEPPLRIIDE------------- 335
            ....|.|:.....|.|.|.|:.      |.|...:...|... ||.:.:|::
Worm   308 QGAHLKIHNVNENDLGTYKCEANNIKAKSYHTIHLREANAPA-EPKVTLIEDKRHSIIWKVESID 371

  Fly   336 -------------------------HERDVGDRYYKSGS 349
                                     .:.|:.|.|:||.|
Worm   372 RDPDLPMTAVEIRHLRAGTAEASGVSDEDISDAYWKSHS 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	19/97 (20%)
		Ig	<258..326	CDD:299845	16/82 (20%)
		IGc2	<417..461	CDD:197706
rig-3	NP_509155.1	IG_like	48..142	CDD:214653	20/100 (20%)
rig-3	NP_509155.1	Ig	267..341	CDD:319273	18/89 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900