DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr18 and igcm-2

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001362087.1	Gene:	igcm-2 / 180913	WormBaseID:	WBGene00020130	Length:	802	Species:	Caenorhabditis elegans

Alignment Length:	273	Identity:	51/273 - (18%)
Similarity:	90/273 - (32%)	Gaps:	81/273 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   244 LNCRVGMLKDKTVMWVRRTAEKVSLLTVGNVTYSGDPRIRVKFQYPNNWRLLINPTQTEDAGVYM 308
            |.|.:.:..:::.....|...::.|...|.......|.::.:........:.|:.....|||||.
Worm    33 LPCSISLFNEESFSLDWRKDGQLILSAFGQEQGHVTPTLQGRLARDGFLGITIHSVTDGDAGVYQ 97

  Fly   309 CQVS------THPPRVFTTNLTVLEPPLRIIDEHERDVGDRYYKSGSTVDLQCQISRS-----FF 362
            |.|:      |.|.:..:..|.|..||:.|.......:   :.|.|:.:..:|:...:     .:
Worm    98 CIVTKFSKQPTRPEKGLSAKLVVNVPPVIISPSKNAII---HKKVGADLIFECKAEGAPSPEITW 159

  Fly   363 QKERQTILKSTDSANDAVQKLIN--------ETTSELNLIGNVNQTQHKFSGQDLEKYFTK---- 415
            .:..|.|      :...|..|.|        .|...:|:.||        |...::..|||
Worm   160 SRNEQII------STSPVLTLSNLEEGDKGLYTCLAVNIEGN--------STSSIDVRFTKATIL 210

  Fly   416 ----------------------------FITWAKDEEPLQGMTNRRLSVSDVWLTSRISIGDAKL 452
                                        ..:|..:::|::        .:.:.|.|.|..||..|
Worm   211 DLIPLNKTVIEGSNVFWHCHANAQATAISYSWLFEKKPIK--------TTSLGLRSNIRSGDLSL 267

  Fly   453 -----SDSGNYSC 460
                 ||||.|:|
Worm   268 QDVRKSDSGWYTC 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	17/86 (20%)
		Ig	<258..326	CDD:299845	15/73 (21%)
		IGc2	<417..461	CDD:197706	14/49 (29%)
igcm-2	NP_001362087.1	IG_like	23..101	CDD:214653	13/67 (19%)
		Ig	124..200	CDD:386229	15/92 (16%)
		IG_like	214..298	CDD:214653	14/75 (19%)
		Ig_3	309..371	CDD:372822
		Ig	389..467	CDD:386229
		FN3	476..548	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900