DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr18 and Dscam

DIOPT Version :9

Sequence 1:NP_573102.1 Gene:dpr18 / 32572 FlyBaseID:FBgn0030723 Length:519 Species:Drosophila melanogaster
Sequence 2:XP_038943864.1 Gene:Dscam / 171119 RGDID:619992 Length:2034 Species:Rattus norvegicus


Alignment Length:607 Identity:117/607 - (19%)
Similarity:205/607 - (33%) Gaps:197/607 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 YRTLSPASNAAQTLPLSYNSQTSLSLLRLLTIALVIGSQVQV-----LYTTSVE----------- 55
            ::.:.|:|..|....:|:...         |::||.||:..:     ||...|:           
  Rat   143 FKCIIPSSVEAYVTVVSWEKD---------TVSLVSGSRFLITSTGALYIKDVQNEDGLYNYRCI 198

  Fly    56 TKSPSASEQSRNGENRSLLFDDYNKTKSTLSTADYLSATRATLYAFSSQDQDEDHSQMPIEASNA 120
            |:.....|..::...|..:.|..|...|.|...|:..|...            ...::|.:|...
  Rat   199 TRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAG------------QRVELPCKALGH 251

  Fly   121 PHSPIPTKMSRGKIPMETPGSMEFSSNSLPIKNVGTTDQLTTVTMPTTAFASLKV-DRSTMKQPI 184
            |....  :..:..:|:|..|..:.:...|.|:|...:|..:.|...:..:.:.|| .|..:|||:
  Rat   252 PEPDY--RWLKDNMPLELSGRFQKTVTGLLIENSRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPL 314

  Fly   185 DSTRTRNHWTASGFARVTE--RPRSKHHHEHHW---GPFFEEPINSATSG--------DNLVSA- 235
            .:|.:.....:|..::|:.  ........|..|   |.......|...:|        |::|.: 
  Rat   315 KATISPRKVKSSVGSQVSLSCSVTGNEDQELSWYRNGEILNPGKNVRITGLNHANLIMDHMVKSD 379

  Fly   236 ------------------------------VHLFTEAVLN--------CRVGMLKDKTVMW---- 258
                                          :..|:|.|::        |.|......||.|    
  Rat   380 GGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLVCNVKGTPLPTVTWTLDD 444

  Fly   259 ---VRRTAEKVS--LLTVGNVTYSGDPRIRVKFQYPNNWRLLINPTQTEDAGVYMCQVSTHPPRV 318
               ::.:..::|  :.:.|||.           .|.|     |:.:|..|.|||.|..:.....|
  Rat   445 DPILKGSGHRISQMITSEGNVV-----------SYLN-----ISSSQVRDGGVYRCTANNSAGVV 493

  Fly   319 -FTTNLTVLEP----PLRIIDE--------HERDVGDRY-----YKSGSTVDL-QCQISRSFFQK 364
             :...:.|..|    |::.|..        |.|.:|..|     ||:.:.:.. ..|::     .
  Rat   494 LYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNANLLPFNHRQVA-----F 553

  Fly   365 ERQTILKSTDSANDAVQKLINETTSELNLIG----NVNQTQH---------------KFS-GQ-- 407
            |....||.:|     |||.::|.....|::.    :.:|:.|               :|| ||  
  Rat   554 ENNGTLKLSD-----VQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRV 613

  Fly   408 ---------DLEKYFTKFITWAKDEEPLQGMTNRRLSVSDVWLTSRISIGDAKLSDSGNYSCSLG 463
                     ||.  .|  |||.||..|:.....  :::.::..||.:.|.:..|..:|||:|   
  Rat   614 FIPCVVVSGDLP--IT--ITWQKDGRPIPASLG--VTIDNIDFTSSLRISNLSLMHNGNYTC--- 669

  Fly   464 RLFTVIVQVQVLTGELPAAVQH 485
                       :.....|||:|
  Rat   670 -----------IARNEAAAVEH 680

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr18NP_573102.1 IG_like 242..325 CDD:214653 20/100 (20%)
Ig <258..326 CDD:299845 15/77 (19%)
IGc2 <417..461 CDD:197706 13/43 (30%)
DscamXP_038943864.1 Ig 26..121 CDD:416386
Ig strand A' 33..37 CDD:409353
Ig strand B 40..49 CDD:409353
Ig strand C 55..61 CDD:409353
Ig strand C' 63..66 CDD:409353
Ig strand D 72..75 CDD:409353
Ig strand E 80..85 CDD:409353
Ig strand F 98..106 CDD:409353
Ig strand G 109..121 CDD:409353
Ig 125..210 CDD:416386 14/75 (19%)
Ig strand A 126..130 CDD:409353
Ig strand A' 132..136 CDD:409353
Ig strand B 139..149 CDD:409353 0/5 (0%)
Ig strand C 157..163 CDD:409353 1/5 (20%)
Ig strand C' 164..167 CDD:409353 1/2 (50%)
Ig strand E 179..185 CDD:409353 2/5 (40%)
Ig strand F 191..201 CDD:409353 1/9 (11%)
IGc2 239..300 CDD:197706 11/74 (15%)
Ig strand B 242..246 CDD:409353 0/3 (0%)
Ig strand C 255..259 CDD:409353 0/5 (0%)
Ig strand F 290..295 CDD:409353 1/4 (25%)
Ig 313..395 CDD:416386 11/81 (14%)
Ig strand A 314..319 CDD:409353 1/4 (25%)
Ig strand A' 322..326 CDD:409353 0/3 (0%)
Ig strand B 329..339 CDD:409353 1/9 (11%)
Ig strand C 344..350 CDD:409353 2/5 (40%)
Ig strand C' 351..354 CDD:409353 1/2 (50%)
Ig strand E 368..374 CDD:409353 0/5 (0%)
Ig strand F 381..389 CDD:409353 0/7 (0%)
Ig 406..501 CDD:416386 22/110 (20%)
Ig strand A 406..409 CDD:409353 0/2 (0%)
Ig strand A' 415..419 CDD:409353 2/3 (67%)
Ig strand B 422..431 CDD:409353 1/8 (13%)
Ig strand C 436..442 CDD:409353 3/5 (60%)
Ig strand C' 444..447 CDD:409353 0/2 (0%)
Ig strand D 452..460 CDD:409353 1/7 (14%)
Ig strand E 464..473 CDD:409353 5/24 (21%)
Ig strand F 480..488 CDD:409353 4/7 (57%)
Ig strand G 491..501 CDD:409353 1/9 (11%)
Ig 504..593 CDD:416386 21/98 (21%)
Ig strand A 505..507 CDD:409353 0/1 (0%)
Ig strand A' 512..516 CDD:409353 1/3 (33%)
Ig strand B 519..526 CDD:409353 1/6 (17%)
Ig strand C 533..539 CDD:409353 0/5 (0%)
Ig strand C' 540..542 CDD:409353 0/1 (0%)
Ig strand D 549..553 CDD:409353 1/8 (13%)
Ig strand E 557..563 CDD:409353 2/5 (40%)
Ig strand F 571..579 CDD:409353 1/7 (14%)
Ig strand G 583..593 CDD:409353 2/9 (22%)
Ig 596..686 CDD:416386 25/105 (24%)
Ig strand A 597..599 CDD:409353 0/1 (0%)
Ig strand B 611..620 CDD:409353 1/8 (13%)
Ig strand C 625..632 CDD:409353 4/10 (40%)
Ig strand C' 634..636 CDD:409353 0/1 (0%)
Ig strand D 643..648 CDD:409353 0/4 (0%)
Ig strand E 651..658 CDD:409353 3/6 (50%)
Ig strand F 665..673 CDD:409353 4/21 (19%)
Ig strand G 676..685 CDD:409353 4/5 (80%)
Ig_DSCAM 689..784 CDD:409397
Ig strand B 707..711 CDD:409397
Ig strand C 720..724 CDD:409397
Ig strand E 749..753 CDD:409397
Ig strand F 763..768 CDD:409397
Ig strand G 777..780 CDD:409397
Ig_DSCAM 785..884 CDD:409398
Ig strand B 805..809 CDD:409398
Ig strand C 818..822 CDD:409398
Ig strand E 848..852 CDD:409398
Ig strand F 862..867 CDD:409398
Ig strand G 875..878 CDD:409398
FN3 885..978 CDD:238020
FN3 986..1083 CDD:238020
FN3 1091..1184 CDD:238020
FN3 1189..1278 CDD:238020
Ig_3 1287..1363 CDD:404760
Ig strand B 1303..1307 CDD:409353
Ig strand C 1316..1320 CDD:409353
Ig strand E 1342..1346 CDD:409353
Ig strand F 1356..1361 CDD:409353
FN3 1380..1470 CDD:238020
FN3 1486..1555 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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