DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr18 and Opcml

DIOPT Version :9

Sequence 1:NP_573102.1 Gene:dpr18 / 32572 FlyBaseID:FBgn0030723 Length:519 Species:Drosophila melanogaster
Sequence 2:XP_017450901.1 Gene:Opcml / 116597 RGDID:620635 Length:354 Species:Rattus norvegicus


Alignment Length:239 Identity:55/239 - (23%)
Similarity:78/239 - (32%) Gaps:85/239 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   230 DNLVSAVHLFTEAVLNCRVGMLKDKT--VMWVRRTAEKVSLLTVGNVTYSGDPRIRVKFQYPNNW 292
            ||:  .|.....|.|.|.:   .|:.  |.|:.|:    ::|..||..:|.|||:.:....|..:
  Rat    43 DNV--TVRQGESATLRCTI---DDRVTRVAWLNRS----TILYAGNDKWSIDPRVIILVNTPTQY 98

  Fly   293 RLLINPTQTEDAGVYMCQVST-HPPRVFTTNLTVLEPPLRIIDEHERDVGDRYYKSGSTVDLQCQ 356
            .::|......|.|.|.|.|.| :.|:....:|.|..|| :|::..    .|.....||:|.|.|.
  Rat    99 SIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPP-QIMNIS----SDITVNEGSSVTLLCL 158

  Fly   357 ISRSFFQKERQTILKSTDSANDAVQKLINETTSELNLIGNVNQTQHKFSGQDLEKYFTKFITWAK 421
                                                .||....|                :||  
  Rat   159 ------------------------------------AIGRPEPT----------------VTW-- 169

  Fly   422 DEEPLQGMTNRRLSVSD----VWLTSRISIGDAKLSDSGNYSCS 461
                      |.|||.:    |.....:.|.|.|...||.|.||
  Rat   170 ----------RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECS 203

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr18NP_573102.1 IG_like 242..325 CDD:214653 24/85 (28%)
Ig <258..326 CDD:299845 19/68 (28%)
IGc2 <417..461 CDD:197706 13/47 (28%)
OpcmlXP_017450901.1 Ig 44..132 CDD:416386 26/96 (27%)
Ig strand A' 44..49 CDD:409353 2/6 (33%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 1/6 (17%)
FR2 64..70 CDD:409353 2/5 (40%)
Ig strand C 64..70 CDD:409353 2/5 (40%)
CDR2 71..83 CDD:409353 4/15 (27%)
Ig strand C' 72..76 CDD:409353 0/7 (0%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 9/33 (27%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 2/8 (25%)
FR4 125..132 CDD:409353 1/6 (17%)
Ig_3 135..206 CDD:404760 27/138 (20%)
Ig strand A 135..138 CDD:409353 2/3 (67%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 4/44 (9%)
Ig strand C 165..170 CDD:409353 3/32 (9%)
Ig strand C' 171..174 CDD:409353 1/2 (50%)
Ig strand F 198..206 CDD:409353 4/6 (67%)
Ig_3 223..300 CDD:404760
putative Ig strand A 224..230 CDD:409353
Ig strand B 240..244 CDD:409353
Ig strand C 253..257 CDD:409353
Ig strand E 279..283 CDD:409353
Ig strand F 293..298 CDD:409353
Ig strand G 306..309 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.