DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr18 and si:ch211-264f5.6

DIOPT Version :9

Sequence 1:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	XP_002665524.2	Gene:	si:ch211-264f5.6 / 100319064	ZFINID:	ZDB-GENE-081104-208	Length:	540	Species:	Danio rerio

Alignment Length:	328	Identity:	71/328 - (21%)
Similarity:	117/328 - (35%)	Gaps:	97/328 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 TVMWVRRTAEKVSLLTVGNVTYSGDPRIRVKFQYPN-------NWRLLINPTQTEDAGVYMCQVS 312
            ||.|.....:.::::||    ......:.|:..|.|       .::|.:.|...||.|.|:..:.
Zfish    53 TVTWTFNKGQPIAMVTV----IPSSNTVSVRPPYVNRISCNRTTFQLQLGPLVKEDTGEYILTIV 113

  Fly   313 THPPRVFT--TNLTVLEP--PLRIIDEHERDVGDRYYKSGSTVDLQCQISRSFFQKERQTILKST 373
            |:...:.|  .:|.||||  .::|.......|     :..|||.|.|....||..|
Zfish   114 TNNGDLVTGQIDLEVLEPVTDVKISSNVLEPV-----EFNSTVVLTCSAKGSFTYK--------- 164

  Fly   374 DSANDAVQKLINETTSELNLIGN------VNQTQHK-----------FSGQD------------- 408
             ..|.:|..:::.|..:||.:||      |.:|..:           .||:.
Zfish   165 -WINGSVPLVVDGTHMQLNAVGNELKISEVRRTDLQGPIVCIAENALESGKSAPFNLTVSYGPEN 228

  Fly   409 -----------LEKYFTKFITWAKDEEP---LQGMTNR-RLSVSDVWLTSRISIGDAKLSDSGNY 458
                       |:|..|..:|...|..|   :|.:.|. .|..:.|...:..::.:.:..:||||
Zfish   229 ILMNQFPTDTYLKKGSTLTLTCTADSNPPATIQWVFNGVNLPSNAVSSPANFTLNNLEEKNSGNY 293

  Fly   459 SC---------SLGRLFTVIVQVQVLTGELPAAVQHNIGSRTEIYSLAMLGHLLVLIFLFTCLKT 514
            :|         .:......:..|:.|:|.       ||.|.|   ||.:.|:..|.:   ||...
Zfish   294 TCVAYNAQTKRYIASRVAFVTVVESLSGT-------NISSST---SLLIAGNSTVNL---TCFAA 345

  Fly   515 ENR 517
            ..|
Zfish   346 AGR 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	17/78 (22%)
		Ig	<258..326	CDD:299845	15/76 (20%)
		IGc2	<417..461	CDD:197706	12/56 (21%)
si:ch211-264f5.6	XP_002665524.2	Ig	33..129	CDD:299845	17/79 (22%)
		IG_like	33..128	CDD:214653	17/78 (22%)
		Ig	130..222	CDD:299845	23/106 (22%)
		IG_like	149..222	CDD:214653	19/82 (23%)
		I-set	233..315	CDD:254352	15/81 (19%)
		Ig_2	235..315	CDD:290606	15/79 (19%)
		IGc2	335..398	CDD:197706	4/17 (24%)
		Ig_2	427..494	CDD:290606
		IG_like	427..479	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910