DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment dpr18 and negr1

DIOPT Version :9

Sequence 1:NP_573102.1 Gene:dpr18 / 32572 FlyBaseID:FBgn0030723 Length:519 Species:Drosophila melanogaster
Sequence 2:XP_031755650.1 Gene:negr1 / 100127726 XenbaseID:XB-GENE-987949 Length:388 Species:Xenopus tropicalis


Alignment Length:354 Identity:80/354 - (22%)
Similarity:116/354 - (32%) Gaps:93/354 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   230 DNLVSAVHLFTEAVLNC--RVGMLKDKTVMWVRRTAEKVSLLTVGNVTYSGDPRIRVKFQYPNNW 292
            ||||  |.....|:|.|  ..|..|.   .|:.|:    |::..|...:|.|||:.:.......:
 Frog    47 DNLV--VRQGETAMLRCFLEEGASKG---AWLNRS----SIIFAGGDKWSVDPRVSIATSSKQEY 102

  Fly   293 RLLINPTQTEDAGVYMCQVST-HPPRVFTTNLTVLEPPLRIIDEHERDVGDRYYKSGSTVDLQC- 355
            .|.|......|.|.|.|.|.| |.||....:|||...| :|.|..    .|.....|:.|.|.| 
 Frog   103 SLRIQKVDVSDDGPYTCSVQTEHSPRTLQVHLTVHVSP-KIYDIS----SDMTVNEGTNVSLICL 162

  Fly   356 ------------QISRSFFQKERQTILK----STDSAND------------AVQKLINETTSELN 392
                        .||.|..|......|.    :.|.|.|            .|:| :..|.:...
 Frog   163 ATGKPEPSISWRHISPSAKQFGSGQYLDIYGITRDQAGDYECSAENDVSFPDVKK-VKVTVNFAP 226

  Fly   393 LIGNVNQTQHKFSGQDLEKYFTKFI-----TWAKDEEPLQGMTN--RRLSVSDVWLTSRISIGDA 450
            .|..:..|........|.:..|..:     .|.|.|:.|   ||  |.:.:.:....|.:::.:.
 Frog   227 TILEITPTGVSLGRTGLIRCETAAVPAPVFEWYKGEKKL---TNGQRGIRIQNYNTRSILTVSNV 288

  Fly   451 KLSDSGNYSC----SLGRLFTVIVQVQVLTGE---------------------------LPAAVQ 484
            .....|||:|    .||.....:...|::...                           .|:..|
 Frog   289 TEEHFGNYTCVAVNKLGTSNASLPLNQIIEPSTTSPVTSSAKYSVKHYARSSSDKPHYAAPSTAQ 353

  Fly   485 HNIGSRTEI-----YSLAMLGHLLVLIFL 508
            :.|..|.||     |.:..|.....:|:|
 Frog   354 YGITGRAEILFSCWYLVLTLSSFTSIIYL 382

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr18NP_573102.1 IG_like 242..325 CDD:214653 25/85 (29%)
Ig <258..326 CDD:299845 21/68 (31%)
IGc2 <417..461 CDD:197706 12/54 (22%)
negr1XP_031755650.1 Ig 44..136 CDD:416386 30/97 (31%)
FR1 44..62 CDD:409353 7/16 (44%)
Ig strand A' 47..53 CDD:409353 5/7 (71%)
Ig strand B 55..63 CDD:409353 3/7 (43%)
CDR1 63..68 CDD:409353 1/4 (25%)
FR2 69..75 CDD:409353 2/8 (25%)
Ig strand C 69..74 CDD:409353 2/7 (29%)
CDR2 76..87 CDD:409353 2/14 (14%)
Ig strand C' 78..82 CDD:409353 0/3 (0%)
Ig strand C' 84..87 CDD:409353 0/2 (0%)
FR3 88..122 CDD:409353 9/33 (27%)
Ig strand D 91..98 CDD:409353 1/6 (17%)
Ig strand E 101..107 CDD:409353 1/5 (20%)
Ig strand F 114..122 CDD:409353 3/7 (43%)
CDR3 123..127 CDD:409353 2/3 (67%)
Ig strand G 127..136 CDD:409353 3/8 (38%)
FR4 129..136 CDD:409353 1/6 (17%)
Ig_3 140..208 CDD:404760 16/72 (22%)
Ig strand A' 146..151 CDD:409353 1/8 (13%)
Ig strand B 157..164 CDD:409353 3/6 (50%)
Ig strand C 170..175 CDD:409353 0/4 (0%)
Ig strand C' 177..179 CDD:409353 1/1 (100%)
Ig strand E 187..193 CDD:409353 1/5 (20%)
Ig strand F 200..207 CDD:409353 1/6 (17%)
Ig strand G 214..222 CDD:409353 2/8 (25%)
Ig_3 226..302 CDD:404760 16/78 (21%)
putative Ig strand A 226..232 CDD:409353 1/5 (20%)
Ig strand B 242..246 CDD:409353 1/3 (33%)
Ig strand C 255..259 CDD:409353 0/3 (0%)
Ig strand E 281..285 CDD:409353 1/3 (33%)
Ig strand F 295..300 CDD:409353 3/4 (75%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 46 1.000 Domainoid score I11916
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

Return to query results.
Submit another query.